000			03364nam a22003855i 4500
001			75912
003			ES-MaUEC
005			20230207040202.0
007			cr nn 008mamaa
008			121116s2013 xxua s 001 0 eng d
020			_a9781461455592
024	7		_a10.1007/978-1-4614-5559-2 _2doi
040			_aES-MaUEC
050		4	_aRC346 _b.K56 2013 EB
082	0	4	_a612.8
100	1		_aKing, Steven R. _984632 _0Local
245	1	0	_aNeurosteroids and the Nervous System _cby Steven R. King
264		1	_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (VI, 125 p.) _b17 ilustraciones, 6 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aSpringerBriefs in Neuroscience _x2191-558X
505	0		_ag 14.) ; t Neurosteroids and Convulsant Activity -- g 14.1.) ; t Anticonvulsant Effects of Neurosteroids -- g 14.2.) ; t Pro-Convulsant Effects of Neurosteroids -- g 15.) ; t Roles in Tumors -- g 16.) ; t Neurosteroids and the Spinal Cord -- g 16.1.) ; t Protective and Restorative Functions of Neurosteroids in Injury -- g 16.2.) ; t Neurosteroids in Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS) -- g 17.) ; t Neurosteroids and the PNS -- g 17.1.) ; t Schwann Cells and Myelination -- g 17.2.) ; t Protective and Regenerative Roles in Injury -- g 17.3.) ; t Demyelinating Diseases and Diabetic Neuropathy -- g 18.) ; t Adrenal Chromaffin Cells and PC12 Cells -- g 19.) ; t Integrated Actions of Neurosteroids in Nociception -- g 19.1.) ; t 3[alpah]-Reduced Steroids and Thermal and Inflammatory Pain -- g 19.2.) ; t Allopregnanolone and Neuropathic Pain -- g 19.3.) ; t DHEA, DHEA-S, and Pregnenolone Sulfate -- g 19.4.) ; t Ovarian Steroids -- g 20.) ; t Mineralocorticoids and Glucocorticoids -- g 20.1.) ; t Glucocorticoids -- g 20.2.) ; t Aldosterone -- g 21.) ; t Substance Abuse -- g 22.) ; t Summary and Conclusions
520			_aWhile steroids from the periphery have profound effects on the nervous system, the nervous system also produces its own steroids de novo. The physiological importance of neurosteroids is beginning to be understood. These steroids potentially have roles in sedative/hypnotic behavior, anxiety, learning, and memory. At the cellular level, neurosteroids affect neuronal excitability, synaptic plasticity and cell proliferation and survival. Early findings hold promise for future strategies to treat specific psychologicalconditions and neurological diseases. This Brief will focus on the current state of understanding of brainderived neurosteroids.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisado
650		7	_aSistema nervioso _xEnfermedades _0comprobar BNE19901058565 _2embne _9169088
830		0	_aSpringerBriefs in Neuroscience _x2191-558X _9133171 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-5559-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781461455592
907			_a.b12815305 _b28-10-17 _c01-10-14
998			_am _a_alco _a_vill _b14-09-17 _cm _dz _ei _feng _gxxu _h0
945			_aRC346 .K56 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11544685 _z06-04-17
999			_c75912 _d75912 _x1