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001			75900
003			ES-MaUEC
005			20230207040202.0
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007			cr nn 008mamaa
008			121206s2013 xxu| s |||| 0|eng d
020			_a9781461452607
024	7		_a10.1007/978-1-4614-5260-7 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC280.B6 _bA382 2013 EB
245	0	0	_aAdvances in Biology and Therapy of Multiple Myeloma _nVolume 2, _pTranslational and Clinical Research _cedited by Nikhil C. Munshi, Kenneth C. Anderson
260			_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (X, 287 p.) _b7 ilustraciones, 5 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aT cell responses in myeloma -- Novel antigenic targets for immunotherapy in myeloma -- Antibody-based therapies in Multiple Myeloma -- Defining multiple myeloma as a target for DNA gene fusion vaccines -- Harnessing allogeneic immunity for anti-myeloma response -- Dendritic cell and peptide-based vaccination in myeloma -- New Proteasome inhibitors -- Newer Imids -- New agents in myeloma -- Early Combination Studies in MM -- The effect of novel antimyeloma agents on bone metabolism -- Index.
520	3		_aDespite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.
988			_aEBOOK, EBSPRINGERrevisado
650		7	_aHuesos _xTumores _9182468 _0comprobar BNE19901362136 _2embne
650		7	_aMieloma múltiple _0comprobar BNE20021387571 _2embne _9160182
700	1		_aAnderson, Kenneth C _eeditor literario _946459
700	1		_aMunshi, Nikhil C. _eeditor literario _984566 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-5260-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12815184 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aRC280 .B6 A382 2013 EB _cV. 2 _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11544569 _z06-04-17
998			_dz _ea _feng _gxxu _h0