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020 _a9781461450702
040 _aES-MaUEC
050 4 _aQR189
_b.I46 2013 EB
245 0 0 _aImmunomic Discovery of Adjuvants and Candidate Subunit Vaccines
_cedited by Darren R. Flower, Yvonne Perrie
260 _aNew York
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (X, 314 p.)
_b51ilustraciones, 34 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aImmunomics Reviews:, An Official Publication of the International Immunomics Society
_v5
505 0 _aIntroduction -- Bacterial genomes and vaccine design -- Identification of candidate vaccine antigens in silico -- Post-Genomic Antigen Discovery: Bioinformatical Approaches to Reveal Novel T-Cell Antigens of Mycobacterium Bovis -- Genome-based Computational Vaccine Discovery by Reverse Vaccinology -- Computational prediction of protein subcellular localization, genomic islands, and virulence to aid antigen discovery -- On the development of Vaccine Antigen Databases: Progress, Opportunity, and Challenge -- What have Dendritic Cells ever done for adjuvant design?Âållular and Molecular Methods for the Rational Development of Vaccine Adjuvants -- Towards the Rational Discovery of Adjuvants -- Designing liposomes as vaccine adjuvants -- Enhancing the delivery and potency of antigens using non-ionic based vesicles -- Immune stimulating complexes (ISCOMs) and Quil-A containing particulate formulations as vaccine delivery systems -- Formulation and characterisation of PLGA microspheres as vaccine adjuvants -- Powder Vaccines for Pulmonary Delivery.
520 _aVaccine discovery is one of the most exciting and fast-moving areas of applied science. Since Edward Jennerâ€{u3837}ork in the 18th century, vaccines have transformed health across the globe. Bringing together clinical, experimental, and computational disciplines vaccinology addresses the most pressing needs of 21st century health-care: the great infectious diseases threatening the developing world, such as HIV, Malaria, and TB; and chronic diseases, such as dementia, threatening the developed world. This volume seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisado
650 7 _aVacunas
_0comprobar BNE19900984775
_2embne
_9140409
700 1 _aPerrie, Yvonne
_eeditor literario
_984610
_0Local
700 1 _aFlower, Darren R.
_eeditor literario
_984611
_0Local
830 0 _aImmunomics Reviews:, An Official Publication of the International Immunomics Society
_v5
_9133166
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-5070-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9781461450702
907 _a.b12815123
_b10-10-17
_c01-10-14
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_b17-03-17
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