000			02985nam a22003735i 4500
001			75889
003			ES-MaUEC
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007			cr nn 008mamaa
008			121206s2013 xxu| s |||| 0|eng d
020			_a9781461449669
040			_aES-MaUEC
050		4	_aQH324.2 _b.S97 2013 EB
245	0	0	_aSystems Biology of Tuberculosis _cedited by Johnjoe McFadden, Dany J.V. Beste, Andrzej M. Kierzek
260			_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XV, 226 p.) _b33 ilustraciones, 28 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aForeword -- Modeling Mycobacterium tuberculosis H37Rv in silico -- Software Platform for Metabolic Network Reconstruction of Mycobacterium tuberculosis -- Probing Gene Regulatory Networks to Decipher Host-Pathogen Interactions -- Metabolism of Mycobacterium tuberculosis -- Protein-protein interaction in the �cs era: Understanding Mycobacterium tuberculosis function -- A systems biology approach for understanding granuloma formation and function in tuberculosis -- Stochastic gene expression in bacterial pathogens: a mechanism for persistence? -- Drug Discovery -- Diagnosis -- Index.
520			_aTuberculosis remains one of the worldâ€{u3822}iggest killers responsible for more than a million deaths each year. New drugs and new vaccines are urgently needed to tackle the disease. This book describes the application of this centuryâ€{u3826}irst new science, systems biology, to the study of tuberculosis. After introducing the basic principles of systems biology, successive chapters describe how systems-based approaches provide new insights into gene regulation, metabolism, protein-protein interaction, host-pathogen interactions, the immune response, persistence, drug treatment and diagnosis of tuberculosis. This book will be an invaluable aid to anyone interested in exploring how the latest science is helping us to understand this ancient disease.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisado
650		7	_aBioinformática _0comprobar BNE20022028248 _2embne _9160489
650		7	_aTuberculosis _9140389 _0comprobar BNE19900984506 _2embne
700	1		_aMcFadden, Johnjoe. _eeditor literario _984599 _0Local
700	1		_aBeste, Dany J. V. _eeditor literario _0Local _984600
700	1		_aKierzek, Andrzej M. _eeditor literario _0Local _984601
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-4966-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781461449669
907			_a.b1281507x _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b17-03-17 _cm _dz _ea _feng _gxxu _h0
945			_aQH324.2 .S97 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11544454 _z06-04-17
999			_c75889 _d75889 _x1