000			03238nam a22003495i 4500
001			75841
003			ES-MaUEC
005			20230207040159.0
007			cr nn 008mamaa
008			120829s2013 xxu| s |||| 0|eng d
020			_a9781461439035
040			_aES-MaUEC
050		4	_aQP625.A27 _bA36 2013 EB
245	0	0	_aAdenosine : _bA Key Link between Metabolism and Brain Activity _cedited by Susan Masino, Detlev Boison
260			_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XVI, 680 p.)
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
520			_aHomeostasis of key metabolites and metabolic health affects all bodily systems. Â{uEBF4}t surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system â€{u0A6E}cluding developmental disorders, acute nervous system injury, and neurodegenerative disorders.Â{u0063}cordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions.Â{u026E}creasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition.Â{u0064}enosine:Â{u0060}Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system.Â{u00A5}cause of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism.Â{u0074} the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression.Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function. Â{uC961}aders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders.This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisado
650	0	7	_aReceptores de adenosina _0LocalV _2embne _9668551
650		7	_aHomeostasis _9144968 _0comprobar BNE19913482041 _2embne
700	1		_aMasino, Susan. _eeditor _942042
700	1		_aBoison, Detlev _eeditor literario _984513 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-3903-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781461439035
907			_a.b12814593 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b22-03-17 _cm _dz _eu _feng _gxxu _h0
945			_aQP625.A27 A36 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11543978 _z06-04-17
999			_c75841 _d75841 _x1