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| 003 | ES-MaUEC | ||
| 005 | 20230202101747.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 120917s2013 xxu| s |||| 0|eng d | ||
| 020 | _a9781461437222 | ||
| 040 | _aES-MaUEC | ||
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_aRB147.5 _b.M58 2013 EB |
|
| 245 | 0 | 0 |
_aMitochondrial Disorders Caused by Nuclear Genes _cedited by Lee-Jun C. Wong. |
| 260 |
_aNew York _bSpringer International Publishing _c2013 |
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| 300 | _a1 recurso en línea (XII, 369 p.) 32 il., 20 il. col. | ||
| 336 |
_aTexto (visual) _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 520 | _aMitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells.Â{u026E} addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes.Â{u04E9}nce mitochondria are present in every cell, every tissue, mitochondrial disorders usually affects multiple organs. Mitochondrial Disorders Caused by Nuclear Genes discusses the biochemical, molecular, clinical, and genetic aspects of complex dual genome mitochondrial disorders. Chapters include genes involved in mitochondrial DNA biogenesis and maintenance of mitochondrial DNA integrity, complex subunits and assembly genes, and mitochondrial protein translation related diseases. | ||
| 942 |
_2lcc _cLE |
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| 988 | _aEBOOK, EBSPRINGERrevisado | ||
| 650 | 0 | 7 |
_aPatología mitocondrial _2embne _9414723 |
| 700 | 1 |
_aWong, Lee-Jun C. _eeditor _984509 _0Local |
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| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-3722-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 901 | _ai9781461437222 | ||
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_a.b1281457x _b10-10-17 _c01-10-14 |
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