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020 _a9781461436973
040 _aES-MaUEC
050 4 _aRC268.4
_b.E44 2013 EB
245 0 0 _aEmerging Concepts of Tumor Exosome-Mediated Cell-Cell Communication
_cedited by Huang-Ge Zhang
260 _aNew York
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (VII, 220 p.) 34 il., 20 il. col.
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
520 _aTumor exsome-mediated cell-cell communication has grown increasingly important in cancer research. Recent findings on vesicle-based information transfer by exosomes have changed our view of the tumor microenvironment. Â{u3D72}rrently, exosomes represent the main extracellular processes implicated in the regulation of multiple physiological processes. Importantly, in cancer, exosomes contribute to the formation of the tumor microenvironment, promoting invasion, angiogenesis, immune regulation and metastasis. Therefore, exosomes could be considered one of the major forces acting locally or systemically to promote the continuous crosstalk between the tumor and its microenvironment, influencing the behavior of different cell types such as stromal, endothelial and bone marrow-derived cells. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. This volume gives a comprehensive review on current research in this area and also discuss future prospects as prognostic markers for cancer.
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisado
650 7 _aCáncer
_xAspectos genéticos
_9273952
_0comprobar BNE19990911214
_2embne
700 1 _aZhang, Huang-Ge
_eeditor literario
_984508
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-3697-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9781461436973
907 _a.b12814568
_b10-10-17
_c01-10-14
998 _am
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_a_vill
_b10-03-17
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945 _aRC268.4 .E44 2013 EB
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