000 02548nam a22003495i 4500
999 _c75836
_d75836
_x1
001 75836
003 ES-MaUEC
005 20230202101746.0
007 cr nn 008mamaa
008 120829s2013 xxu| s |||| 0|eng d
020 _a9781461436768
040 _aES-MaUEC
050 4 _aRC268.44.P16
_bP45 2013 EB
245 0 0 _ap53 in the Clinics
_cedited by Pierre Hainaut, Magali Olivier, Klas G. Wiman
260 _aNew York
_bSpringer International Publishing
_c2013
300 _a1 recurso en línea (X, 358 p.)
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
520 _aWith over 60,000 referenced publications, p53 has emerged as one of the most important factors in human cancer. Research on p53 has led to a complete overhaul of our understanding of the molecular basis of human cancer. In recent years, these major advances in knowledge are starting to impact on cancer management and therapy. This book thus captures a critical turning point in p53 research, from basic to translational research and clinical application. p53 in the Clinics follows the success ofÂ{u0CB5} Years of p53 Research and condensates in a series of authoritative chapters the considerable progress on the applications of p53 into the clinics and the substantial advances on diseases caused by inheritance of p53 defects, on somatic p53 mutations as biomarkers in molecular pathology, on progress in gene therapy and on developments of innovative drugs and clinical trials. This volume will appeal to a wide audience of students and professionals in basic and clinical cancer research and treatment, and will highlight the exciting “next stepsâ€{u0A6E} p53 research and applications.
650 0 7 _aCáncer
_9273952
_2embne
_xAspectos genéticos
700 1 _aHainaut, Pierre
_eeditor
_0Local
_984503
700 1 _aOlivier, Magali
_eeditor literario
_984504
_0Local
700 1 _aWiman, Klas G
_eeditor literario
_984505
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4614-3676-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9781461436768
907 _a.b12814544
_b10-10-17
_c01-10-14
942 _2lcc
_cLE
945 _aRC268.44.P16 P45 2013 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11543929
_z06-04-17
988 _aEBOOK, EBSPRINGERrevisado
998 _am
_a_alco
_a_vill
_b22-03-17
_cm
_dz
_eu
_feng
_gxxu
_h0