000			02026nam a22003375i 4500
001			75814
003			ES-MaUEC
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007			cr nn 008mamaa
008			120905s2013 xxu| s |||| 0|eng d
020			_a9781441999672
040			_aES-MaUEC
050		4	_aRC268.5 _b.E65 2013 EB
245	0	0	_aEpigenetic Alterations in Oncogenesis _cedited by Adam R. Karpf
260			_aNew York _bSpringer International Publishing _c2013
300			_a1 recurso en línea (XV, 348 p.) 22 il. col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v754
520			_aThe purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “aboveâ€{u09E5}netics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGERrevisado
650		7	_aCarcinogénesis _0comprobar BNE19923478372 _2embne _9146492
700	1		_aKarpf, Adam R. _eeditor. _984455 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4419-9967-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781441999672
907			_a.b12814325 _b10-10-17 _c01-10-14
998			_am _a_alco _a_vill _b22-03-17 _cm _dz _eu _feng _gxxu _h0
945			_aRC268.5 .E65 2013 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1154370x _z06-04-17
999			_c75814 _d75814 _x1