000			02670nam a22003615i 4500
999			_c75769 _d75769
001			75769
003			ES-MaUEC
005			20240108170256.0
007			cr nn 008mamaa
008			100301s2006 ne | s |||| 0|eng d
020			_a9781402047091
040			_aES-MaUEC
050		4	_aQP517.C45 _bS633 2006 EB
082	0	4	_a611.01816
245	0	0	_aSmad Signal Transduction : _bSmads in Proliferation, Differentiation and Disease _cedited by Peter ten Dijke, Carl-Henrik Heldin
260			_aDordrecht _bSpringer International Publishing _c2006
300			_a1 recurso en línea (XIII.473 p.)
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aProteins and Cell Regulation _v5
520			_aFor the first time world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in tissue homeostasis. In a series of 22 cutting-edge chapters forward looking reviews of Smads are provided that cover their discovery, evolution, role in development, mechanism of action and regulation, and how deregulation in Smad signalling contributes to human diseases. Written for an audience with basic understanding of molecular and cell biology, this volume provides an in-depth review of a rapidly developing field and extensive cross-references between chapters are provided. This book will be of particular interest to basic and applied biomedical researchers (students, post-docs or group leaders) with desire to understand the principles of cell-cell communication and mechanisms by which signaling pathways and gene programs control cell proliferation and differentiation, and how this knowledge may come to be applied in the clinic.
650		7	_aTransducción de la señal celular _2embne _9689361
700	1		_aDijke, Peter ten _eeditor literario _984369 _0Local
700	1		_aHeldin, Carl-Henrik _eeditor literario _984370 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/1-4020-4709-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781402047091
907			_a.b12813874 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aQP517.C45 S633 2006 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11543255 _z06-04-17
988			_aEBOOK, EBSPRINGERrevisado
998			_am _a_alco _a_vill _b13-02-17 _cm _dz _ef _feng _gne _h0