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020 _a9781402039591
040 _aES-MaUEC
050 4 _aR856
_b.G464 2006 EB
082 0 4 _a571.6
245 0 0 _aGenetic Engineering of Mesenchymal Stem Cells
_cedited by Jan A Nolta
260 _aDordrecht, Netherlands
_bSpringer International Publishing
_c2006
300 _a1 recurso en línea (VI, 170 p.)
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
338 _aonline resource
_bcr
_2rdacarrier
520 _aMSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGERrevisado
650 7 _9143820
_aIngeniería biomédica
_0comprobar BNE19902550170
_2embne
700 1 _aNolta, Jan A
_eeditor literario
_984283
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/1-4020-3959-X
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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_b10-10-17
_c01-10-14
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_b03-01-17
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