000			02669nam a2200349 c 4500
999			_c75640 _d75640 _x1
001			75640
003			ES-MaUEC
005			20230207040151.0
008			160712s2006 mau| s |||| 0|eng d
020			_a9780387310473
040			_aES-MaUEC
050		4	_aRM411 _b.N49 2006 EB
245	0	0	_aNew concepts of antiviral therapy _cedited by Andreas Holzenburg, Elke Bogner
260			_aBoston _bSpringer International Publishing _c2006
300			_a1 recurso en línea (XIX, 538 p.)
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
338			_aonline resource _bcr _2rdacarrier
520			_aAntiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA). Highlights of this book include the discussion of: - novel, promising compounds - concepts of therapy for new/emerging viruses - managing drug resistance - new therapeutic strategies This book presents an overview of the most recent developments. Contributions were carefully selected to ensure quality coverage by acknowledged experts over a wide spectrum and should prove to be of great value to students and serve as a compendium for R and D and educational professionals.
650	0	7	_aAntivirales _9677566 _2embne
650	0	7	_aBacterias _9138901 _2embne
700	1		_aHolzenburg, Andreas _eeditor literario _984142 _0Local
700	1		_aBogner, Elke _eeditor literario _984143 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-0-387-31047-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9780387310473
907			_a.b12812584 _b10-10-17 _c01-10-14
942			_2lcc _cLE
945			_aRM411 .N49 2006 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11541969 _z06-04-17
988			_aEBOOK, EBSPRINGERrevisado
998			_am _a_alco _a_vill _b12-07-16 _cm _dz _ef _feng _gmau _h0