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_aQH585.2 _b.A55 2011 EB |
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| 082 | 0 | 4 | _a571.6/381 |
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_aAnimal cell culture : _bessential methods _ceditor, John M. Davis |
| 260 |
_aChichester, West Sussex _aHoboken, NJ _bWiley-Blackwell _c2011 |
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_a1 recurso en línea (XXVII, 346 p.), [2] h. de lám. _bil. |
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_aTexto (visual) _btxt _2rdacontent |
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_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 504 | _aBibliografía | ||
| 520 | 3 | _aAnimal cell culture is a widely used technology for producing recombinant proteins. The ability to make post-translational modifications and secrete the active forms of the protein into the culture medium represents major advantages over other processes. The growing market demand for pharmaceuticals has created a need for increased production capacity; however, achieving productivity gains in both the upstream stage and downstream processes can subject cells to aggressive environments such as those involving hydrodynamic stresses. Although numerous studies have explored the consequences of cell damage due to hydrodynamic stress, there has been a lack of understanding of the mechanism of such damage at a cellular level. Cell damage can also influence biomedical applications. Cells manipulated in instruments such as diagnosis and analysis devices can experience hydrodynamic forces. | |
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| 988 | _aEBNETLUEM, EBOOK | ||
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_aCélulas _0LocalT _2embne _9139475 |
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_aCélulas _0LocalT _2embne _9139475 |
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_aDavis, John _d1952- _eeditor literario _933048 _0comprobar BNE20012260538 |
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_uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&lang=es&db=nlebk&db=nlabk&site=eds-live&AN=391253 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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