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040 _aUIU
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050 4 _aQH585.2
_b.A55 2011 EB
082 0 4 _a571.6/381
245 0 0 _aAnimal cell culture :
_bessential methods
_ceditor, John M. Davis
260 _aChichester, West Sussex
_aHoboken, NJ
_bWiley-Blackwell
_c2011
300 _a1 recurso en línea (XXVII, 346 p.), [2] h. de lám.
_bil.
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
504 _aBibliografía
520 3 _aAnimal cell culture is a widely used technology for producing recombinant proteins. The ability to make post-translational modifications and secrete the active forms of the protein into the culture medium represents major advantages over other processes. The growing market demand for pharmaceuticals has created a need for increased production capacity; however, achieving productivity gains in both the upstream stage and downstream processes can subject cells to aggressive environments such as those involving hydrodynamic stresses. Although numerous studies have explored the consequences of cell damage due to hydrodynamic stress, there has been a lack of understanding of the mechanism of such damage at a cellular level. Cell damage can also influence biomedical applications. Cells manipulated in instruments such as diagnosis and analysis devices can experience hydrodynamic forces.
942 _2lcc
_cLE
988 _aEBNETLUEM, EBOOK
650 0 7 _aCélulas
_0LocalT
_2embne
_9139475
650 0 7 _aCélulas
_0LocalT
_2embne
_9139475
700 1 _aDavis, John
_d1952-
_eeditor literario
_933048
_0comprobar BNE20012260538
856 4 0 _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&lang=es&db=nlebk&db=nlabk&site=eds-live&AN=391253
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9780470669822
907 _a.b11981404
_b10-10-17
_c12-11-12
998 _am
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_b30-01-13
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