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020 _a9783031475672
024 7 _a10.1007/978-3-031-47567-2
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRS400-431
_b2023 EB
245 0 0 _aRespiratory Delivery of Biologics, Nucleic Acids, and Vaccines
_cedited by Jenny Lam, Philip Chi Lip Kwok
250 _a1st ed. 2023
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aAAPS Introductions in the Pharmaceutical Sciences
_x2522-8358 ;
_v8
505 0 _aChapter 1: Design strategies of dry powders for pulmonary delivery of pharmaceutical peptides -- Chapter 2. Pulmonary delivery of antibody for the treatment of respiratory diseases -- Chapter 3: Dry powder formulation of monoclonal antibodies for pulmonary delivery -- Chapter 4: Antimicrobial peptides and proteins for inhalation -- Chapter 5: Pulmonary delivery of nucleic acids -- Chapter 6: Intranasal and inhaled vaccines -- Chapter 7: Respiratory delivery of probiotics to improve lung health -- Chapter 8: Respiratory delivery of bacteriophages for the treatment of lung infections -- Chapter 9: Pharmacokinetics of inhaled medications - what do we know about biological macromolecules?.
520 _aTherapeutic macromolecules and biologics have gained increasing importance in the last decade. Pulmonary and intranasal delivery of these therapeutic modalities, which have poor oral bioavailability, could constitute an attractive, non-invasive alternative to parenteral delivery. They can be considered for either topical use for treating diseases affecting the airways or for systemic use for treating a variety of other diseases. Therefore, this book is a readable, thoughtful, and useful guide on the latest research developments and the best options that people involved with pulmonary and intranasal route of administration and biologically active agents can bring to their practices. Furthermore, it explores the underlying scientific rationale for the strategies applied to overcome drug delivery challenges and provides insights to inspire further research in this growing area.
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-47567-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
988 _aSpringer_Medicine_2023
999 _c402939
_d402939