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020 _a9783031456541
024 7 _a10.1007/978-3-031-45654-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC254-282
_b2023 EB
245 0 0 _aEpigenetics in Oncology
_cedited by Jianjun Chen, G Greg Wang, Jun Lu
250 _a1st ed. 2023
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aCancer Treatment and Research
_x2509-8497 ;
_v190
505 0 _aPART I RNA Epigenetics, RNA modifications in cancer metabolism and tumor microenvironment -- RNA modifications in cancer stem cell biology -- Recent advances of RNA m6A modifications in cancer immunoediting and immunotherapy -- Recent advances in RNA m6A modification in solid tumors and tumor immunity -- Recent advances in adenosine-to-inosine RNA editing in cancer -- RNA modification in hematopoietic malignancies -- PART II Histone Epigenetics, The SWI/SNF complex: A frequently-mutated chromatin remodelling complex in cancer -- Histone readers and their roles in cancer -- Polycomb repressive complex 2 in oncology -- Epigenetic (de)regulation in prostate cancer -- PART III DNA Epigenetics, TET methylcytosine dioxygenases in cancer -- Inferring the cancer cellular epigenome heterogeneity via DNA methylation patterns.
520 _aThis book addresses Epigenetics in Cancer and covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years. Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively. By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resourcefor scientists, graduate students and clinicians alike. .
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-45654-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
988 _aSpringer_Medicine_2023
999 _c402884
_d402884