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999			_c402762 _d402762
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003			ES-MaUEC
005			20240629115202.0
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008			231028s2023 sz | fo |||| 0|eng d
020			_a9783031391712
024	7		_a10.1007/978-3-031-39171-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH671 _b2023 EB
245	0	0	_aFerroptosis in Health and Disease _cedited by Daolin Tang
250			_a2nd ed. 2023
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1. Lipid Metabolism and Homeostasis in Ferroptosis -- Chapter 2. Iron Metabolism and Ferroptosis -- Chapter 3. Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy -- Chapter 4. The Role of Autophagy in Ferroptosis -- Chapter 5. Heat Shock Proteins and HSF1 in Ferroptosis -- Chapter 6. The Ongoing Search for a Biomarker of Ferroptosis -- Chapter 7. p53 and Ferroptosis -- Chapter 8. Ferroptosis in Cardiovascular Disease -- Chapter 9. Understanding Ferroptosis from a Free Radical Perspective -- Chapter 10. The NRF2-anti-ferroptosis Axis in Health and Disease -- Chapter 11. Epigenetic Modification in Ferroptosis -- Chapter 12. Organelle-specific Mechanisms of Ferroptosis -- Chapter 13. Ferroptosis: A Promising Therapeutic Target for Cardiovascular Diseases -- Chapter 14. Ferroptosis in Central Nervous System Hypoxia-Ischemia -- Chapter 15. Involvement of Ferroptosis in Lupus Nephritis -- Chapter 16. Ferroptosis and Infectious Diseases -- Chapter 17. Selenium Metabolic Pathway in Ferroptotic Cell Death -- Chapter 18. Epigenetic and Post-Translational Regulation of Ferroptosis -- Chapter 19. Phospholipid Peroxidation in Health and Disease -- Chapter 20 -- PKC{esc}(Sb{esc}(BII-ACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases -- Chapter 21. Cancer Treatment with Ferroptosis by a Combination of Iron Nanoparticles and Gene Therapy -- Chapter 22. Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimer's Disease.
520			_aThis updated and expanded volume gives new insights on ferroptosis - an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway. Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2. This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases.
988			_aSpringer_Medicine_2023
650		7	_2embne _9160237 _aMuerte celular
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-39171-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b06/2024 _dz _ean _zSI