000			03355nam a22003015i 4500
001			402663
003			ES-MaUEC
005			20240528105918.0
007			cr nn 008mamaa
008			230926s2023 sz | o |||| 0|eng d
020			_a9783031397219
024	7		_a10.1007/978-3-031-39721-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC648-665.2 _b2023 EB
245	0	0	_aObesity, Diabetes and Inflammation : _bMolecular Mechanisms and Clinical Management _cedited by Dimiter Avtanski, Leonid Poretsky
250			_a1st ed. 2023
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aContemporary Endocrinology _x2523-3793
505	0		_aInflammation: Pathogenesis and Biological Markers -- Obesity and Inflammation -- Inflammation and Diabetes Mellitus -- Diabetes, Obesity, and Oxidative stress -- Advanced Glycation End-Products and Diabetes -- Genetic and Epigenetic Basis of Obesity-Induced Inflammation and Diabetes -- Inflammation and Vascular Pathologies -- Environmental and Lifestyle Factors Influencing Inflammation and Type 2 Diabetes Onset -- Inflammation in Pregnant Women with Obesity and Gestational Diabetes -- Potential Pharmaceutical and Non-Pharmaceutical Approaches to Obesity and Diabetes: Focus on Inflammation.
520			_aObesity is a worldwide epidemic that affects half a billion people. It has been estimated that, if current trends continue, by 2050, 60% of men and 50% of women worldwide will be obese. Hypertrophy and hyperplasia of white adipose tissue caused by overweight and obesity lead to a chronic inflammatory state, which results in impaired insulin sensitivity and the development of diabetes. Currently, the number of people affected by diabetes globally exceeds 400 million (rising more rapidly in low- and middle-income countries). In 2019, diabetes was the ninth leading cause of mortality, with an estimated 1.5 million direct deaths. This book provides a comprehensive overview of the relationship between inflammation, obesity, and diabetes. It focuses on the pathogenesis and biological mechanisms of obesity, the interaction between adipose tissue and the immune system, the role of genetic and environmental factors, the progression of cardiovascular complications, and the associationof obesity and inflammation with type 1 and type 2 diabetes, as well as gestational diabetes. This volume also includes practical recommendations for preventing and managing these conditions using both lifestyle modifications and pharmacological interventions. Written by experts in the field, Obesity, Diabetes and Inflammation: Molecular Mechanisms and Clinical Management addresses the role of inflammation in both obesity and diabetes, its effect on vascular and non-vascular pathologies, oxidative stress, genetics, and epigenetics. This text aims to be a valuable resource for researchers, clinicians, and students of medicine at all levels. .
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-39721-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aSpringer_Medicine_2023
999			_c402663 _d402663