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020 _a9783031315015
024 7 _a10.1007/978-3-031-31501-5
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP572 .S4
_b2023 EB
245 0 0 _aTestosterone :
_bFrom Basic to Clinical Aspects
_cedited by Alexandre Hohl
250 _a2nd ed. 2023
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aThe History of Testosterone: From Antiquity to Modern Times -- Testosterone: Molecules and Receptors -- Physiology of Male Gonadotropic Axis and Disorders of Sex Development -- Utility and Limitations in Measuring Testosterone -- Male Puberty: What Is Normal and Abnormal? -- Gynecomastia -- Hypogonadotropic and Hypergonadotropic Hypogonadism -- Functional Hypogonadism -- Male Hypogonadism and Aging -- Male Hypogonadism and Traumatic Brain Injury -- Male Hypogonadism and Fertility -- Anabolic Steroid-Induced Hypogonadism -- Testosterone Therapy: Oral, Buccal and Nasal Androgens -- Testosterone Therapy: Transdermal Androgens -- Testosterone Therapy: Injectable Androgens -- Benefits and Adverse Events of Testosterone Therapy -- Testosterone and Sexual Function -- Testosterone Therapy and Prostate -- Testosterone and Cardiovascular Effects -- Testosterone and Women -- Transgender Care and Testosterone Hormone Therapy -- Testosterone and Endocrine Disruptors -- Testosterone Misuse and Abuse.
520 _aEven though research on testosterone is increasing, there is still much controversy regarding its physiology and clinical use. This book provides a broad overview on testosterone, from its basic features to the most recent evidence of clinical applicability. In addition, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. The testes are vital organs for reproduction of the human species, besides being the main source of testosterone production in men. Although not essential for survival, these singular structures represent the essence of male biological function. Testosterone is the most important testicular androgen in men. Low serum testosterone levels are associated with cardiovascular morbidity, metabolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Also, there is increasing evidencethat serum testosterone is a major biomarker status of men's health in general. Hypogonadism in a male refers to a decrease in one or both of the two major functions of the testes: sperm production or testosterone production. These abnormalities can result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism). Currently, the clinical features of male hypogonadism are sufficiently well-recognized, the causes are well-known, and the tests of the hypothalamic-pituitary-testicular axis are accurate enough for the diagnosis in most patients. Testosterone, the focus hormone of this book, is used in different forms and routes of administration. Several authors unravel its peculiarities and assist in choosing the most suitable form in each case, as well as the possible risks of its misuse or even abuse in men and women, seeking alternatives to help patients in this situation.
988 _aSpringer_Medicine_2023
650 7 _2embne
_9675054
_aHormonas sexuales
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-31501-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b06/2024
_dz
_eb
_zSI