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020 _a9783031175725
024 7 _a10.1007/978-3-031-17572-5
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQR186
_b2023 EB
245 0 0 _aManagement of Dysregulated Immune Response in the Critically Ill
_cedited by Zsolt Molnar, Marlies Ostermann, Manu Shankar-Hari
250 _a1st ed. 2023
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aLessons from the ICU, Under the Auspices of the European Society of Intensive Care Medicine
_x2522-5936
505 0 _aForeword -- Preface -- Part I. The Host Immune Response -- Phenotypes -- The Dysregulated Host Response -- What is Cytokine Storm? -- Hemophagocytic Lymphohistiocytosis -- Extracorporeal Circulation Related Immune response -- Vasoplegic Shock -- Part II. Assessing Dysregulated Immune Response at the Bedside -- Pro- and anti-inflammatory biomarkers -- How to interpret procalcitonin? -- Assessment of the macro-, and microcirculation -- Part III. Dysregulated Immune Response and organ dysfunction -- Heart and circulation -- Brain -- Kidneys -- Liver -- Hemostasis -- The muscles -- Part IV. Modulating the immune response -- The Role of Steroids -- Why did Anti-Cytokine Therapies Fail in the Past? -- Extracorporeal cytokine removal.
520 _aThis book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.
988 _aSpringer_Medicine_2023
650 7 _2embne
_9162846
_aRespuesta inmune
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-17572-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b06/2024
_dz
_eb
_zSI