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020 _a9789811976308
024 7 _a10.1007/978-981-19-7630-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC280 .B8
_b2023 EB
245 0 0 _aScreening and Risk Reduction Strategies for Breast Cancer :
_bImaging Modality and Risk-Reduction Approaches
_cedited by Masakazu Toi
250 _a1st ed. 2023
264 1 _aSingapore
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _a1. Introduction of the whole issue -- 2. Breast cancer epidemiology: incidence, risks and subtype -- 3. Personalized genetic breast cancer risk estimation with polygenic risk scores -- 4. Mathematical model forassessing breast cancer risk -- 5. Cost-effectiveness Analysis of multigene testing -- 6. Hereditary breast cancer: Its biology, subtype and clinical phenotype -- 7. Surgical risk reduction of breast cancer -- 8. Medical risk reduction of breast cancer -- 9. Screening for breast cancer with mammography -- 10. Breast cancer screening: Weighing the benefits and harms -- 11. Breast cancer screening according to individual risk -- 12. MRI: Detection of noninvasive diseases -- 13. Significance of MRI for women having dense breasts -- 14. Ultrasound: screening of breast cancer -- 15. Detection of breast cancer by PET -- 16. Radiowave mammography -- 17. Photoacoustic imaging of breast cancer.
520 _aThis book provides readers with the most up-to-date practical information on breast cancer screening. Since breast cancers are highly heterogeneous, time to clinical onset from the initial carcinogenesis differs diversely between cancers. Pathological germline variants and driver mutations cause a high lifetime risk of breast cancer. The lifetime risks are various according to what genes are pathologically dysfunctional. Integrated omics and imaging technologies have established varying tumour characteristics. Thus, this book suggests that a more individualised scheme is required to improve breast cancer screening. A key aim is to demonstrate how multiple diagnostic imaging modalities such as mammography, ultrasonography, MRI, PET and dbPET improve breast cancer screening accuracy. Mammography screening alone may have a limited impact on breast cancer risk prediction. These issues are crucial to discuss. Clinical experts recommend that new modalities be incorporated for women with dense breasts, like ultrasonography, dynamic mammography, MRI and maybe breast-dedicated PET. Topics on these modalities are going to be summarized in this book. An in-depth review of these modalities is summarised in this book. In addition, new diagnostic modalities, including risk assessment tools, multi-cancer early detection tests using liquid biopsy, the role of protein biomarkers in breast cancer risk screening, challenges, and hopes for future advances, are also covered in this book.
988 _aSpringer_Medicine_2023
650 7 _2embne
_9182522
_aMamas
_xCáncer
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-19-7630-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b06/2024
_dz
_eb
_zSI