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003			ES-MaUEC
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008			230526s2023 sz | eo |||| 0|eng d
020			_a9783031295416
024	7		_a10.1007/978-3-031-29541-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRM301.5 _b2023 EB
245	0	0	_aAdvances in Pharmacokinetics and Pharmacodynamics _cedited by Panos Macheras
250			_a1st ed. 2023
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAAPS Introductions in the Pharmaceutical Sciences _x2522-8358 _v9
505	0		_aPharmacokinetics -- Chapter 1: Current status in PBPK modeling -- Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment -- Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development -- Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications -- Pharmacodynamics -- Chapter 5: Pharmacokinetic - Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies -- Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body -- Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation.
520			_aThis book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9145145 _aFarmacocinética
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-29541-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b04/2024 _dz _eb _zSI