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008			230301s2023 si | o |||| 0|eng d
020			_a9789811982491
024	7		_a10.1007/978-981-19-8249-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRS431 .P75 _b2023 EB
245	0	0	_aProtein-based Therapeutics _cedited by Dev Bukhsh Singh, Timir Tripathi
250			_a1st ed. 2023
264		1	_aSingapore _bSpringer Nature Singapore _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1_Introduction to Protein Therapeutics. -- Chapter 2_Clinical Applications of Protein-based Therapeutics Against Various Diseases. -- Chapter 3_Protein Engineering Methods for the Design of Protein Therapeutics -- Chapter 4_Recombinant Production of Therapeutic Proteins -- Chapter 5_Antibodies as Protein Therapeutics -- Chapter 6_Streptokinase: The Success Story of a Therapeutic Protein -- Chapter 7_Strategies for Formulation and Systemic Delivery of Therapeutic Proteins -- Chapter 8_Approved Protein Therapeutics and Their Biochemical Targets -- Chapter 9_Pharmacogenetic Biomarkers of Protein Therapeutics -- Chapter 10_Immunogenicity of Therapeutic Proteins -- Chapter 11_Efficacy and Safety Issues of Therapeutic Proteins -- Chapter 12_Emerging Trends, Challenges, and Opportunities in Protein Therapeutics -- Chapter 13_Biosimilar, Biobetter & Biosuperior Therapeutic Proteins -- Chapter 14_Therapeutic Protein-based Vaccines.
520			_a This book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases. It presents the latest advancements in protein engineering techniques for producing desirable therapeutic proteins. The book also covers the strategies used to formulate and deliver systemic therapeutic proteins, approved protein therapeutics and their targets, and pharmacogenetic biomarkers. Further, it discusses challenges associated with the clinical implications of therapeutic proteins, including safety, immunogenicity, protein stability, degradation, and efficacy. It illustrates the development of biosimilar antibodies, optimization strategies for producing biobetter antibodies, and presents fundamental concepts about biosuperior therapeutics. Lastly, it includes a discussion about protein-based vaccines against bacterial and viral infections.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9139861 _aProteínas _xUso terapéutico
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-19-8249-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b04/2024 _dz _eb _zSI