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008			230920s2023 si | o |||| 0|eng d
020			_a9789819915606
024	7		_a10.1007/978-981-99-1560-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRA1226 _b2023 EB
100	1		_aIshido, Masami _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9690220
245	0	0	_aHealth Risk Assessment of Environmental Chemicals _bPre-Emptive and Integrated Approaches _cby Masami Ishido
250			_a1st ed. 2023.
264		1	_aSingapore _bSpringer Nature Singapore _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1. Introduction -- Chapter 2. The safe dose in the utilization of chemicals -- Chapter 3. Carcinogens -- Chapter 4. Endocrine disruptors -- Chapter 5. Nanomaterials -- Chapter 6. Epigenetic chemicals -- Chapter 7. Toward the integrated Health risk assessment of chemicals -- Chapter 8. Expanded toxicological mechanisms of chemicals -- Chapter 9. Fields and exposure periods -- Chapter 10. Environmental chemicals as plasticity disruptors -- Chapter 11. It began with the pharmacological evaluation of endocrine disruptors -- Chapter 12. Integration of health risk assessment for various chemicals: Common biomarkers in different exposure routes -- Chapter 13. Toward a dimension-free, pre-emptive, integrated health risk assessment of chemicals -- Chapter 14. Inheritance of neurological disorders -- Chapter 15. Epigenetics -- Chapter 16. Environmental epigenetics.
520			_aThis book presents the frontier research of toxicology and health risk assessment of chemicals. First, it provides an overview of the current methods of evaluating safety amounts of chemicals and provides a new aspect of the principle of toxicology. Secondly, it shows recent research where the new method of health risk evaluation is adopted, followed by an integrated health risk assessment of chemicals. Finally, it describes the epigenetic inheritance of chemical impact on health throughout several generations. Estimating the safety amount of chemicals surrounding our lives is not sufficient for health risk evaluation, particularly for carcinogenic compounds, endocrine disruptors, and nano materials. The author's group has found a family of chemicals linked to ADHD through animal screening and identified its chemical nature using chemoinformatics methods. Based on these new developments, this book proposes to utilize the biomarker common to those chemicals for health risk assessment, independent of exposure routes and physiological dimensions. The book appeals to researchers and students in the field of toxicology, health risk assessment, pharmacology, and public health. .
988			_aSpringer_BiomedLife_2023
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-99-1560-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b05/2024 _dz _eIG _zSI