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008			230720s2023 si | o |||| 0|eng d
020			_a9789819911837
024	7		_a10.1007/978-981-99-1183-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRD651 _b2023 EB
245	0	0	_aTumor Ecosystem : _bAn Ecological View of Cancer Growth and Survival _cedited by Erwei Song
250			_a1st ed. 2023
264		1	_aSingapore _bSpringer Nature Singapore _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1: Interactions in cancer ecosystem -- Chapter 2: Local niche construction -- Chapter 3: Pre-metastatic niche -- Chapter 4: Emerging concepts in cluster metastasis -- Chapter 5: Neuronal regulation in cancer ecosystem -- Chapter 6: Endocrinal regulation in cancer ecosystem -- Chapter 7: Innate immune system in cancer ecosystem -- Chapter 8: Adaptive immune system in cancer ecosystem -- Chapter 9: Inflammation in cancer ecosystem -- Chapter 10: Metabolic regulation in cancer ecosystem -- Chapter 11: Vascular regulation in cancer ecosystem -- Chapter 12: Microbial interaction in cancer ecosystem -- Chapter 13: Viral interaction in cancer ecosystem -- Chapter 14: Evolution of cancer ecosystem -- Chapter 15: Driving force of cancer ecosystem -- Chapter 16: Modeling, visualizing and subtyping the cancer ecosystem -- Chapter 17: Bio-engineering methods to mimic cancer ecosystem -- Chapter 18: Cancer ecosystem-directed therapeutic strategies.
520			_aThis book intends to report new concept of onco-spheres in cancer ecosystem. Onco-spheres are defined as where cancer cells (living organisms) dynamically interact with nontumor cellular (other living organisms) and noncellular components (non-living environmental factors) in the 'host' internal environment (habitat) to construct a self-sustainable cancer ecosystem, which can be scoped at three different levels: primary/regional, distal and systemic onco-spheres. Cancer cells should be conceived as 'living organisms', interacting with cellular or noncellular components in the host internal environment, not only with the local tumor microenvironment (TME) but also constantly communicating with a distant organ niche as well interacting with the host's nervous, endocrine and immune systems, to construct a self-sustainable 'biosphere', as we termed the tumor ecosystem. By looking at the interaction of cancer and host as a unique ecosystem, we will use ecology principles to further delineate the features of the dynamics of the tumor ecosystem. As the pioneer in proposing this concept, we feel that this full-scale overview of the tumor ecosystem is able to inform the readers about this concept, and to pave the way for designing novel therapeutic strategies on actionable targets within tumor ecosystem. The book is likely to be of interest to immunologist, biologist, medical students, researchers and general public who wish to learn more on this new concept of tumor ecosystem, and how this could be applied in many fields of research.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9139209 _aTumores
650		7	_2embne _9139308 _aCáncer
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-99-1183-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eIG _zSI