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020 _a9783031156403
024 7 _a10.1007/978-3-031-15640-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQR360
_b2023 EB
245 0 0 _aViral Fitness and Evolution :
_bPopulation Dynamics and Adaptive Mechanisms
_cedited by Esteban Domingo, Peter Schuster, Santiago F Elena, Celia Perales
250 _a1st ed. 2023.
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aCurrent Topics in Microbiology and Immunology
_x2196-9965
_v439
505 0 _aTheoretical analysis of the evolution of viral populations in sequence space, and empirical fitness landscapes -- Self-organized maps to derive fitness landscapes from deep sequencing data -- Mutations to overcome viral resistance in plants -- The role of recombination in the generation of new begomovirus phenotypes -- Plant virus adaptation to new hosts -- Viral fitness, host interactions, and resistance to antiviral agents -- Viral fitness and evolution of hepatitis C virus -- Population dynamics and fitness variations of hemorrhagic RNA viruses -- Coronavirus genome sequences, variation, and disease implications -- Epilogue: viral populations from a theoretical and experimental perspective.
520 _aThis book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.
988 _aSpringer_BiomedLife_2023
650 7 _2embne
_9413113
_aVirología
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-15640-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b04/2024
_dz
_ek
_zSI