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020 _a9789819913046
024 7 _a10.1007/978-981-99-1304-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC848.H43
_b2023 EB
245 0 0 _aHepatitis E Virus
_cedited by Youchun Wang
250 _a2nd ed. 2023.
264 1 _aSingapore
_bSpringer Nature Singapore
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aAdvances in Experimental Medicine and Biology
_x2214-8019
_v1417
505 0 _aChapter 1 Hepatitis E Virus -- Chapter 2 Characteristics and Functions of HEV Proteins -- Chapter 3 Epidemiology of Hepatitis E -- Chapter 4 Hepatitis E as a Zoonosis -- Chapter 5 Genetic Evolution of Hepatitis E Virus -- Chapter 6 Transmission of Hepatitis E Virus -- Chapter 7 Immunobiology and Host Response to HEV -- Chapter 8 Cell Culture for hepatitis E virus -- Chapter 9 Stem Cell and organoid culture for hepatitis E virus -- Chapter 10 Lifecycle of hepatitis E Virus -- Chapter 11 Morphogenesis of Hepatitis E Virus -- Chapter 12 Animal Models for Hepatitis E Virus -- Chapter 13 Clinical Manifestations of Hepatitis E -- Chapter 14 Laboratory Diagnosis of HEV Infection -- Chapter 15 Treatment of Hepatitis E -- Chapter 16 Prophylactic Hepatitis E Vaccine -- Chapter 17 Puzzles for hepatitis E virus.
520 _aThis book systematically and comprehensively discusses the biological, epidemiological, and clinical characteristics of the hepatitis E virus (HEV). It presents current knowledge of HEV and explores experimental methods, treatment, and prevention of HEV. First identified in the 1980s and cloned in 1990, HEV is the causative agent of hepatitis E, which mainly occurs in developing regions, such as Southeast Asia, the Middle East, and Africa, and significantly affects the health of the people in these areas. It is estimated that a third of the world's population has been infected with HEV, which is transmitted via the fecal-oral route and can infect both humans and animals. In the second edition, new chapters are added to demonstrate the lifecycle, morphogenesis, and stem cell culture of hepatitis E virus. Although research on hepatitis E virus has made progress recently, there are still some problems that have not been solved. Those problems are discussed in this edition, which would be helpful for researchers to understand the problems on hepatitis E virus that they have faced. Meanwhile, the epidemiology, transmission, genetic evolution, animal models, treatment, and others in the related chapters of the first version were also updated according to the most recent research progress. The book provides an overview of HEV from benchside to bedside. It is a valuable resource for researchers in the field and those in the pharmaceutical industry developing HEV vaccines, as well as physicians involved in identifying and treating those infected with the virus.
988 _aSpringer_BiomedLife_2023
650 7 _2embne
_9142760
_aHepatitis
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-99-1304-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b04/2024
_dz
_ek
_zSI