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020 _a9783031153051
024 7 _a10.1007/978-3-031-15305-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQR400.2.V37
_b2023 EB
245 0 0 _aVaricella-zoster Virus :
_bGenetics, Pathogenesis and Immunity
_cedited by Ann M Arvin, Jennifer F Moffat, Allison Abendroth, Stefan L Oliver
250 _a1st ed. 2023.
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aCurrent Topics in Microbiology and Immunology
_x2196-9965
_v438
505 0 _aVaricella-zoster Virus - Genetics, Molecular Evolution, and Recombination -- The structures and functions of VZV glycoproteins -- Modulation of apoptosis and cell death pathways by Varicella zoster virus -- Modulation of host cell signaling pathways by varicella-zoster virus -- Modulation of MHC and MHC-like molecules by Varicella Zoster Virus -- Varicella Zoster Virus Neuronal Persistence and Reactivation modeled in-vitro -- Humanized Severe Combined Immunodeficient (SCID) Mouse Models for Varicella-Zoster Virus Pathogenesis -- Simian Varicella Virus: Molecular Virology and mechanisms of pathogenesis -- A guide to preclinical models of zoster-associated pain and postherpetic neuralgia -- Immune Responses to Varicella-Zoster Virus Vaccines -- Common features between stroke following varicella in children and stroke following herpes zoster in adults.
520 _aThis edited volume provides insights about the molecular virology, pathoenesis of infection and host responses to varicella-zoster virus, which is a medically important human herpesvirus. The chapters not only discuss genetics and molecular evolution of the virus, but also new structure-based knowledge on the functions of viral glycoproteins. Further, the authors illustrate how mechanisms from the virus are used to take over and remodel host cells during pathogeneis. These mechanisms also enable viral modulation of host cells and evasion of the host immune response. Part of these evasion and survival strategies, is the reaction to triggered host cell responses like autophagy, the stress response, modulation of apoptosis and other cell death pathways. This hands-on knowledge is crucial for students and clinicians in Virology, Immunology, and Infectious Diseases. Chapter "Common features between stroke following varicella in children and stroke following herpes zoster in adults" is available open access under a Creative Commons Attribution 4.0 International License via Springerlink.com.
988 _aSpringer_BiomedLife_2023
650 7 _2embne
_9140445
_aVirus
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-15305-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b04/2024
_dz
_ek
_zSI