000			03491nam a22003375i 4500
999			_c399099 _d399099
001			399099
003			ES-MaUEC
005			20240402090216.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			230911s2023 sz | o |||| 0|eng d
020			_a9783031260988
024	7		_a10.1007/978-3-031-26098-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP363.5 _b2023 EB
100	1		_aten Donkelaar, Hans J. _eautor _4http://id.loc.gov/vocabulary/relators/aut _988911
245	1	0	_aClinical Neuroembryology : _bDevelopment and Developmental Disorders of the Human Central Nervous System _cby Hans J ten Donkelaar, Martin Lammens, Akira Hori
250			_a3rd ed. 2023.
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aOverview of the Development of the Human Brain and Spinal Cord -- Mechanisms of Development -- Causes of Congenital Malformations -- Neurulation and Neurulation Defects -- The Neural Crest and Craniofacial Malformations -- Development and Developmental Disorders of the Spinal Cord -- Development and Developmental Disorders of the Brain Stem -- Development and Developmental Disorders of the Human Cerebellum -- Development and Developmental Disorders of the Forebrain -- Development and Developmental Disorders of the Cerebral Cortex.
520			_aThis book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic/ischaemic causes. The book contains three general, introductory chapters in which an overview of the development of the human brain and spinal cord, a summary of mechanisms of development as obtained in experimental studies in various invertebrates and vertebrates, and an overview of the causes of congenital malformations are presented. The developmental disorders of the human brain and spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These chapters are abundantly illustrated in colour with carefully chosen clinical case studies with imaging data, and when available, postmortem verification of the developmental disorders involved. In the third edition, more emphasis has been given to the developmental ontology based on the prosomeric approach, and fetal development. Prenatal diagnosis by ultrasound, MRI and DTI, and classifications of developmental disorders have been updated. A number of new Clinical Cases have been included. Several new co-authors participate in various chapters. The book is intended for advanced medical students, and all those clinicians working with children and adults with developmental disorders of the CNS. Unique to the book is the integration of data from human embryology, experimental and molecular findings in mice in particular, imaging and developmental neuropathology.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9138462 _aSistema nervioso
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-26098-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b04/2024 _dz _ek _zSI