000			02898nam a2200325 i 4500
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003			ES-MaUEC
005			20240317122702.0
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008			231012s2023 si | o |||| 0|eng d
020			_a9789819924158
024	7		_a10.1007/978-981-99-2415-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH604.2 _b2023 EB
245	0	0	_aTight Junctions in Inflammation and Cancer _cedited by Ajaz A. Bhat, Mohammad Haris, Muzafar A. Macha, Punita Dhawan
250			_a1st ed. 2023
264		1	_aSingapore _bSpringer Nature Singapore _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1. Inflammation and Cancer: Role of Tight Junctions -- Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer -- Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis -- Chapter 4. Imaging techniques to study tight junctions -- Chapter 5. Tight junction proteins as emerging drug targets: Expanding the horizons from inflammation to cancer -- Chapter 6. Tight Junctions and signaling pathways in cancer -- Chapter 7. Molecular architecture and function of tight junctions -- Chapter 8. The role of tight junction proteins in cancer.
520			_aThis book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9667661 _aInteracción celular
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-99-2415-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eb _zSI