000			03163nam a2200337 i 4500
999			_c398985 _d398985
001			398985
003			ES-MaUEC
005			20240317122050.0
006			a|||| o|||| 00| 0
007			cr nn 008mamaa
008			230622s2023 sz | o |||| 0|eng d
020			_a9783031303005
024	7		_a10.1007/978-3-031-30300-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP702 .P6 _b2023 EB
245	0	0	_aHyaluronan : _bStructure, Biology and Biotechnology _cedited by Alberto Passi
250			_a1st ed. 2023.
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aBiology of Extracellular Matrix _x2191-1959 _v14
505	0		_aChapter 1: Biochemistry of hyaluronan synthesis -- Chapter 2: Update on hyaluronan in development -- Chapter 3: Long non-coding RNAs and epigenetic regulation of hyaluronan synthesis -- Chapter 4: The hyaluronan-rich zones of plasma membrane protrusions and extracellular vesicles -- Chapter 5: Hyaluronan in Kidney Fibrosis -- Chapter 6: Inter-α-inhibitor proteins: A review of structure and function -- Chapter 7: CD44: Does CD44v6 adversely impact the prognosis of cancer patients? -- Chapter 8: The pharmacokinetics and pharmacodynamics of 4-methylumbelliferone and its glucuronide metabolite in mice -- Chapter 9: The role of hyaluronan in skin wound healing -- Chapter 10: Sulfated hyaluronan: a novel player in cancer therapeutic and bioengineering approaches.
520			_aThis book addresses the structural and biological properties of the extracellular matrix component and glycosaminoglycan polymer hyaluronan (or hyaluronic acid, HA). The book discusses various aspects of HA biology, e.g., HA synthesis and degradation, as well as the role of HA in embryogenesis, development, and cell maintenance. The reader will learn about the role of HA in different tissues as well as its biological activities triggered by the interaction with different HA receptors. A closer look is had at the involvement of HA in human pathologies such as cancer, kidney fibrosis and wound healing. Biotechnological and biomedical applications for HA such as scaffold generation and drug delivery, including the novel synthetic sulphated HA are explored. This work will appeal to a wide readership within the extracellular matrix and hyaluronan field. It can serve as an introduction to the field for junior scientists but can also help senior scientists to gain a broader view of the field beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9144229 _aPolisacáridos
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-30300-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eb _zSI