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003			ES-MaUEC
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007			cr nn 008mamaa
008			231130s2023 sz | o |||| 0|eng d
020			_a9783031423659
024	7		_a10.1007/978-3-031-42365-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC268.4 _b2023 EB
245	0	0	_aCancer Epigenetics _cedited by Rasime Kalkan
250			_a1st ed. 2023
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aEpigenetics and Human Health _x2191-2270 _v11
505	0		_aPart-1. Background -- Chapter 1. An Overview of Epigenetics Modifications in Normal and Cancer Cell -- Chapter 2. Epigenetic Enzymes and Mutation of Epigenetic Enzymes -- Chapter 3. Introduction to Cancer Epigenetics -- Part II. Cancer Specific Epigenetic Alterations -- Chapter 4. Epigenetics in the Diagnosis, Prognosis and Therapy of Cancer -- Chapter 5. The Clinical Studies and Epi-Drugs In Various Cancer Types -- Chapter 6. Epigenetic Regulation in Breast Cancer Tumor Microenvironment -- Chapter 7. The Epigenetics Of Brain Tumors: Fundamental Aspects Of Epigenetics In Glioma -- Chapter 8. Epigenetic Alterations in Pancreatic Cancer -- Chapter 9. Current Preclinical Applications of Pharmaco-Epigenetics in Cardiovascular Diseases -- Chapter 10. Epigenetic Alterations in Colorectal Cancer -- Chapter 11. Epigenetic Alterations in Hematopoietic Disorders.
520			_aEpigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns. These changes can lead to alterations involved in tumor formation, imprinting, and metabolic disorders. Recent advances can help us understand the importance of epigenetic changes in both cancer development and tumor progression. In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression. Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development. The second part focusses on cancer specific epigenetic alterations and discusses the potential use of epigenetic markers as biomarkers in diagnosis, early cancer progression, and prognosis. Moreover, it reviews the therapeutic potential of epigenetic drugs. Given its scope, Cancer Epigenetics is an indispensable resource not only for researchers working in the field of human epigenetics and cancer research but also for advanced students seeking for an introduction into epigenetic mechanisms. .
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9273952 _aCáncer _xAspectos genéticos
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-42365-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eb _zSI