000			03412nam a2200337 i 4500
999			_c398899 _d398899
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003			ES-MaUEC
005			20240316095233.0
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007			cr nn 008mamaa
008			230724s2023 sz | o |||| 0|eng d
020			_a9783031333255
024	7		_a10.1007/978-3-031-33325-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH442 _b2023 EB
245	0	0	_aGenome Editing in Biomedical Sciences _cedited by Geraldo A. Passos
250			_a1st ed. 2023
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in Experimental Medicine and Biology _x2214-8019 _v1429
505	0		_aWhat is the CRISPR system and how it is used? -- Modern approaches to mouse genome editing using the CRISPR-Cas toolbox and their applications in functional genomics and translational research -- Long Non-Coding RNAs and Crispr-Cas edition in Tumorigenesis -- The Crispr/Cas system in human cancer -- Using CRISPR/Cas9 to Edit a Thyroid Cancer Cell Line -- Genome editing for engineering the next generation of advanced immune cell therapies -- CRISPR Genome Editing and the Study of Chagas Disease -- Genome Editing Tools for Lysosomal Storage Disorders -- CRISPR Libraries and Whole-Genome Screening to Identify Factors for Viral Infections -- Gene Editing Technologies Targeting TFAM and its Relation to Mitochondrial Diseases -- The Gene-Edited Babies Controversy: Reactions in the Scientific Community, Social Media, and the Press -- Index.
520			_aThis volume focuses on applying the Crispr system in editing the genome of human cells (in vitro and in vivo) and model organisms used in biomedical research. With the advent of Crispr technology, genome editing soon became a procedure of great interest to laboratories worldwide due to its relative ease and accuracy. In biomedical sciences, genome editing by Crispr has already enabled the development of new experimental model systems. In medicine, therapeutic alternatives for the genetic "correction" of diseases have already begun to appear. Therefore, the book's purpose is to bring in a single volume, chapters that show the scientific community in biomedicine, medicine, human genetics, oncology, virology, and parasitology, among others, the advances in genomic editing. In a chapter dedicated to the ethical aspects of human genomic editing, we also address what we can and should do with this (bio)technology. The book chapters were written by productive researchers specializing in Crispr genome editing. The chapters cover the concept of Crispr and genome editing and how to use this new methodology in biomedical research and medicine, among other aspects, including the ethical controversy around its use in humans. The writing of the chapters keeps a specialized language intelligible enough for those who want to introduce themselves to the subject.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9141520 _aIngeniería genética
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-33325-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eb _zSI