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003			ES-MaUEC
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007			cr nn 008mamaa
008			240118s2023 sz | o |||| 0|eng d
020			_a9783031411595
024	7		_a10.1007/978-3-031-41159-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH430 _b2023 EB
100	1		_aÁlvarez-Castro, José M. _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9689813
245	1	0	_aGenes, Environments and Interactions : _bEvolutionary and Quantitative Genetics Brought Up-to-date _cby José M. Álvarez-Castro
250			_a1st ed. 2023
264		1	_aCham _bSpringer International Publishing _c2023
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1: Discovering The Genotype -- Chapter 2: The Primeval Theory Of Ge-Netic Effects -- Chapter 3: Genetic Effects Over One Century -- Chapter 4: Hgenetic Architectures At The Individual Level -- Chapter 5: Genetic Effects In Popula-Tions Under Linkage Equilibrium -- Chapter 6: A General Theory Of Genetic Effects -- Chapter 7: Variance Decomposition, Gene Mapping And Average Excesses-Orthogonality In The Spotlight -- Chapter 8: Applied Cases Of Advanced Genetic Modelling -- Chapter 9: The Comes And Goes Of The Black Box Perspective In Quantitative Genetics -- Chapter 10: Addendum: An Acid Test For Noia.
520			_aGenetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.
988			_aSpringer_BiomedLife_2023
650		7	_2embne _9138044 _aGenética
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-41159-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eb _zSI