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020 _a9783031390050
024 7 _a10.1007/978-3-031-39005-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRS431 .R34
_b2023 EB
245 0 0 _aRadiopharmaceutical Therapy
_cedited by Lisa Bodei, Jason S. Lewis, Brian M. Zeglis
250 _a1st ed. 2023.
264 1 _aCham
_bSpringer International Publishing
_c2023
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aPreface -- Foreword -- Section 1. Fundamentals -- Chapter 1. Introduction: The Case for Endoradiotherapy -- Chapter 2. The History of Endoradiotherapy -- Chapter 3. The Nuclear Chemistry of Therapeutic Radionuclides -- Chapter 4. The Production of Therapeutic Radionuclides -- Chapter 5. The Radiobiology of Alpha Particles, Beta Particles, and Auger Electrons -- Chapter 6. The Radiopharmaceutical Chemistry of Metallic Radionuclides -- Chapter 7. The Radiopharmaceutical Chemistry of Non-Metallic Radionuclides -- Chapter 8. Dosimetry in Endoradiotherapy -- Section 2. Deeper Dives -- Chapter 9. Antibodies as Vectors for Endoradiotherapy -- Chapter 10. Case Study #1: 225Ac-Labeled IgG -- Chapter 11. Case Study #2: 131I-3F8 -- Chapter 12. Case Study #3: Antibody Fragments in Endoradiotherapy -- Chapter 13. Peptides as Vectors for Endoradiotherapy -- Chapter 14. Case Study #4: LUTATHERA -- Chapter 15. Case Study #5: CXCR4 -- Chapter 16. Case Study #6: JR11 -- Chapter 17. Small Molecules as Vectors for Endoradiotherapy -- Chapter 18. Case Study #7: PSMA-617 -- Chapter 19. Case Study #8: 223RaCl3 -- Section 3. Special Topics -- Chapter 20. Auger Emitters in Endoradiotherapy -- Chapter 21. In Vivo Pretargeting -- Chapter 22. Theranostic Imaging and Endoradiotherapy -- Chapter 23. The Next Generation of Therapeutic Radionuclides -- Chapter 24. Artificial Intelligence and Machine Learning -- Chapter 25. The Regulatory Review of Radiotherapeutics: USA -- Chapter 26. The Regulatory Review of Radiotherapeutics: Europe -- Chapter 27. The Regulatory Review of Radiotherapeutics: Japan -- Chapter 28. Radiotherapeutics in the Nuclear Pharmacy -- Chapter 29. The Future.
520 _aThis book covers foundational topics in the emerging field of radiopharmaceutical therapy. It is divided into three sections: fundamentals, deeper dives, and special topics. In the first section, the authors examine the field from a bird's-eye view, covering topics including the history of radiopharmaceutical therapy, the radiobiology of radiopharmaceutical therapy, and the radiopharmaceutical chemistry of both metallic and non-metallic radionuclides. The second section provides a more in-depth look at specific radiotherapeutics. Chapters include broader discussions of the different platforms for radiopharmaceutical therapy as well as more focused case studies covering individual radiotherapeutics. The third and final section explores a number of areas for further study, including medical physics, artificial intelligence, in vivo pretargeting, theranostic imaging, and the regulatory review process for radiotherapeutics. This book is the first of its kind and is useful for a broad audience of scientists, researchers, physicians, and students across a range of fields, including biochemistry, cancer biology, nuclear medicine, radiology, and radiation oncology.
988 _aSpringer_BiomedLife_2023
650 7 _2embne
_9141446
_aProductos radiofarmacéuticos
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-39005-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b03/2024
_dz
_eb
_zSI