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003			ES-MaUEC
005			20240311140146.0
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008			240104s2024 sz | o |||| 0|eng d
020			_a9783031513466
024	7		_a10.1007/978-3-031-51346-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH603 .I54 _b2024 EB
245	0	0	_aAnion Channels and Transporters _cedited by Christoph Fahlke
250			_a1st ed. 2024
264		1	_aCham _bSpringer International Publishing _c2024
300			_a1 recurso en línea
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aHandbook of Experimental Pharmacology _x1865-0325 _v283
505	0		_aPreface -- Muscle chloride channels -- Adrenal anion channels - new roles in zona glomerulosa physiology and in the pathophysiology of primary aldosteronism -- ClC-K Kidney Chloride Channels : from structure to pathology -- Biophysical and pharmacological insights to CLC chloride channels and Transporters -- Function and regulation of the calcium-activated chloride channel anoctamin 1 -- Structure and function of calcium-activated chloride channels and scramblases in TMEM16 family -- Structural basis for anion-selective Cys-loop receptor signal transduction and modulation -- Physiological functions of the volume regulated anion channel VRAC/LRRC8 and the proton-activated chloride channel PAC/TMEM206 -- CFTR modulators: from mechanism to targeted therapeutics -- Structure, physiology, and pharmacology of chloride-dependent cation cotransporters -- SLC26 Anion Transporters -- Pharmacology of Na-dependent transporters of inorganic phosphate -- Simulation of fluoride anions in CLC proteins: from potent inhibition to selective transport.
520			_aThis book provides an overview on recent progress in anion channels and transporters. It covers multiple scales of analysis ranging from studying the molecular basis of function at atomic resolution to cellular consequences to channel/transporter dysfunction and approaches to correct such processes by pharmacological intervention. Similar anion channels and transporters are expressed in multiple tissues - often fulfilling similar cellular tasks, but also clearly distinct functions. The aim is to combine work on multiple cell and organ systems.
988			_aSpringer_BiomedLife_2024
650		7	_2embne _9155847 _aCanales iónicos
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-51346-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2024 _dz _eb _zSI