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020 _a9783031428593
024 7 _a10.1007/978-3-031-42859-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRM267
_b2024 EB
245 0 0 _aMacrolides as Immunomodulatory Agents
_cedited by Bruce K. Rubin, Masaharu Shinkai
250 _a1st ed. 2024
264 1 _aCham
_bSpringer International Publishing
_c2024
300 _a1 recurso en línea
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aProgress in Inflammation Research
_x2296-4525
_v92
505 0 _aPart I. Mechanisms of Action and Novel Macrolides -- Macrolides and Diseases Associated with Loss of Epithelial Barrier Integrity -- Macrolides and Inflammatory Cells, Signaling, and Mediators -- Part II. Clinical Use for Airway Disease -- Macrolides as Immunomodulatory Agents -- Macrolides and Cystic Fibrosis -- Non-CF Bronchiectasis -- Macrolide Use in Chronic Obstructive Pulmonary Disease -- Macrolides and Asthma Therapy -- Macrolides and Interstitial Lung Diseases -- Macrolides in Acute Respiratory Distress Syndrome and Acute Lung Injury -- Azithromycin for Other Lung Diseases: Lung Transplantation and Sarcoidosis -- Macrolides for Rhinosinusitis and Nasal Polyps -- Part III. Clinical Use for Other Diseases -- Macrolides for Cancer -- Macrolides in Chronic Skin Disorders -- Macrolide Use in Preschool Aged Children with Acute or Recurrent Respiratory Tract Illnesses with Wheezing -- Macrolides and Immunomodulation: Today and the Future.
520 _aFor over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host and improve clinical status. This book summarizes our current knowledge regarding proposed mechanisms for these properties, established clinical results, and what the future may hold with emphasis on novel clinical applications and the fascinating development of non-antimicrobial macrolides with preserved and enhanced immunomodulatory properties.
988 _aSpringer_BiomedLife_2024
650 7 _2embne
_9138527
_aAntibióticos
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-42859-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b03/2024
_dz
_eb
_zSI