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020 _a9781071619940
024 7 _a10.1007/978-1-0716-1994-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP624.5 .M46
_b2022 EB
245 0 0 _aEpigenome-Wide Association Studies :
_bMethods and Protocols
_cedited by Weihua Guan
250 _a1st edition 2022
264 1 _aNew York, NY
_bSpringer International Publising
_c2022
300 _a1 recurso en línea (X, 229 páginas)
_b63 ilustraciones, 45 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2432
505 0 _aQuantification Methods for Methylation Levels in Illumina Arrays -- Evaluating Reliability of DNA Methylation Measurement -- Accurate measurement of DNA methylation: Challenges and Bias Correction. Using R for Cell-Type Composition Imputation in Epigenome-Wide Association Studies -- Cell Type-Specific Signal Analysis in Epigenome-Wide Association Studies -- Controlling Batch Effect in Epigenome-Wide Association Study -- DNA methylation and Atopic Diseases -- Meta-analysis for Epigenome-Wide Association Studies -- Increase the Power of Epigenome-Wide Association Testing Using ICC-Based Hypothesis Weighting -- A Review of High-dimensional Mediation Analyses in DNA Methylation Studies -- DNA Methylation Imputation across Platforms -- Workflow to mine frequent DNA Co-Methylation Clusters in DNA Methylome Data -- BCurve: Bayesian Curve Credible Bands Approach for Detection of Differentially Methylated Regions -- Predicting chronological age from DNA methylation data: A machine learning approach for small datasets and limited predictors -- Application of Correlation Pre-Filtering Neural Network to DNA Methylation Data: Biological Aging Prediction -- Differential Methylation Analysis for Bisulfite Sequencing (BS-seq) Data.
520 _aThis volume details features of DNA methylation data, data processing pipelines, quality control measures, data normalization, and to discussions of statistical methods for data analysis, control of confounding and batch effects, and identification of differentially methylated regions. Chapters focus on microarray-based methylation measures and sequence-based measures. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary methodologies and software packages, step-by-step, readily reproducible analysis pipelines, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Epigenome- Wide Association Studies: Methods and Protocols: aims to be a useful practical guide to researches to help further their study in this field. .
988 _aSpringer_Protocols_2022
650 7 _2embne
_9670608
_aADN mitocondrial
776 0 8 _iPrinted edition:
_z9781071619933
776 0 8 _iPrinted edition:
_z9781071619957
776 0 8 _iPrinted edition:
_z9781071619964
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1994-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b07/2023
_dz
_eb
_zSI