000 03779nam a2200397 i 4500
999 _c396580
_d396580
001 396580
003 ES-MaUEC
005 20230718082103.0
006 a|||| o|||| 00| 0
007 cr nn 008mamaa
008 220105s2022 xxua o |||| 0|eng d
020 _a9781071620267
024 7 _a10.1007/978-1-0716-2026-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP379
_b2022 EB
245 0 0 _aMeasuring Cerebellar Function
_cedited by Roy V. Sillitoe
250 _a1st edition 2022
264 1 _aNew York, NY
_bSpringer International Publising
_c2022
300 _a1 recurso en línea (XIII, 351 páginas)
_b77 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v177
505 0 _aCerebellar Modeling using Human Induced Pluripotent Stem Cells -- From Cerebellar Genes to Behaviors in Zebrafish -- Silencing the Output of Cerebellar Neurons using Cell Type-Specific Genetic Deletion of Vesicular GABA and Glutamate Transporters -- Mapping Structure-Function Relationships within Cerebellar Circuits -- Designing Behavioral Tasks for Cerebellar Functional Analysis in the Mouse -- Learning Paradigms and Genetic Tools for the Study of Cerebellum-Dependent Learning and Memory -- Neural Circuit Activity Dependent Chromatin Mechanisms in Cerebellar Motor Learning -- In Vitro Voltage Imaging of Subthreshold Activity in Inferior Olive Neurons with ANNINE-6plus -- Mapping Synaptic Connectivity in the Cerebellar Cortex using RuBi-Glutamate Uncaging -- Multisite Extracellular Electrode Neuronal Recordings in the Rodent Cerebellar Cortex and Nuclei -- Investigating Cerebrocerebellar Neuronal Interactions in Freely Moving Mice using Multi-Electrode, Multi-Site Recordings -- In Vivo Optical Detection of Membrane Potentials in the Cerebellum: Voltage Imaging of Zebrafish -- Imaging Neuronal Activity in Cerebellar Cortex of Behaving Mice -- Measuring Cerebellar Processing and Sensorimotor Functions in Non-Human Primates -- Optogenetics in Complex Model Systems (Non-Human Primate) -- Clinical Assessment of the Cerebellum.
520 _aThis volume considers the current techniques used by experts to study and measure cerebellar function. The chapters in this book cover topics such as stem cell-based techniques; conditional genetics approaches in model systems; neuronal recordings conducted in vitro and in vivo; and an ever-growing list of behavioral paradigms. This book also provides readers with a guide for how to use tools such as iPSCs and how to address questions using a range of approaches in animal model systems including mouse, rat, zebrafish, and non-human primate. In the Neuromethods series style, the chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Measuring Cerebellar Function is a valuable resource for cerebellar enthusiasts and other scientists interested in learning more about the cerebellum and the technological advances that are currently being employed to unlock brain function and understand animal behavior.
988 _aSpringer_Protocols_2022
650 7 _9151993
_aCerebelo
776 0 8 _iPrinted edition:
_z9781071620250
776 0 8 _iPrinted edition:
_z9781071620274
776 0 8 _iPrinted edition:
_z9781071620281
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2026-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b07/2023
_dz
_eb
_zSI