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008			211213s2022 xxua o |||| 0|eng d
020			_a9781071615799
024	7		_a10.1007/978-1-0716-1579-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRM301.25 _b2022 EB
245	0	0	_aGreen Chemistry in Drug Discovery : _bFrom Academia to Industry _cedited by Paul F. Richardson
250			_a1st edition 2022
264		1	_aNew York, NY _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XVI, 617 páginas) _b609 ilustraciones, 19 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aGreen Synthesis of Common Heterocycles -- Greener Methods for Amide Bond Synthesis -- Mitsunobu Reactions in Medicinal Chemistry and Development of Practical Modifications -- Direct Nucleophilic Substitution of Alcohols by Brønsted or Lewis Acids Activation: An Update -- Friedel-Crafts Reactions -- Ionic Liquids: Design and Applications -- Designing Efficient Cascade Reactions in Drug Discovery -- Multicomponent Synthesis: Cohesive Integration of Green Chemistry Principles -- Direct C-H Functionalization Approaches to Pharmaceutically Relevant Molecules -- C-H Activation with Photoredox Catalysis -- In Situ Protecting Groups for Chemoselective Transformations -- Expanding the Biocatalysis Toolbox -- New Directions in Coupling Chemistry -- Flow Chemistry as an Enabling Technology for Synthetic Organic Chemistry -- Reaction Optimization: A High-Throughput Experimentation Approach -- Radiopharmaceutical Discovery with 11CO2-Fixation Methods Inspired by Green Chemistry.
520			_aThis detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores greener approaches to chemical transformations that are both prevalent and have been highlighted as challenging within the pharmaceutical industry, overall synthetic strategy, as well as the implementation and impact of a range of enabling technologies within medicinal chemistry. As a volume of the Methods in Pharmacology and Toxicology series, chapters provide the kind of key insight that can guide researchers toward greater success in the lab. Authoritative and practical, Green Chemistry in Drug Discovery: From Academia to Industry provides both a fundamental insight into the progress that has been made as well as some of the challenges that still exist for these techniques to be effectively implemented in the drug discovery process in a routine manner.
988			_aSpringer_Protocols_2022
650		7	_2embne _9183058 _aFarmacología _xInvestigación
776	0	8	_iPrinted edition: _z9781071615775
776	0	8	_iPrinted edition: _z9781071615782
776	0	8	_iPrinted edition: _z9781071620335
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1579-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2023 _dz _eb _zSI