000 04760nam a2200409 i 4500
999 _c396549
_d396549
001 396549
003 ES-MaUEC
005 20230720150102.0
006 a|||| o|||| 00| 0
007 cr nn 008mamaa
008 220808s2022 xxua o |||| 0|eng d
020 _a9781071624937
024 7 _a10.1007/978-1-0716-2493-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP519.9 .C36
_b2022 EB
245 0 0 _aCapillary Electrophoresis-Mass Spectrometry :
_bMethods and Protocols
_cedited by Christian Neusüß, Kevin Jooß
250 _a1st edition 2022
264 1 _aNew York, NY
_bSpringer International Publising
_c2022
300 _a1 recurso en línea (XI, 260 páginas)
_b5 ilustraciones, 4 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2531
505 0 _aEvaluation of prototype CE-MS interfaces -- Capillary Electrophoresis-Mass Spectrometry (CE-MS) by Sheath-Flow Nanospray interface and its use in biopharmaceutical applications -- Protocol for etching bare-fused silica capillaries for sheathless capillary electrophoresis-mass spectrometry coupling -- Microfabricated Liquid Junction Capillary Electrophoresis-Mass Spectrometry Interface -- Successive Multiple Ionic-Polymer Layer Coatings for intact protein analysis by Capillary Zone Electrophoresis - Mass Spectrometry - Application to Hemoglobin Analysis -- On-line Immobilized Enzyme Microreactor Capillary Zone Electrophoresis-Mass Spectrometry for Peptide Mapping -- Bottom up analysis of proteins by peptide mass fingerprinting with tCITP-CZE-ESI-TOF MS after tryptic digest -- Top-down proteomics by capillary zone electrophoresis-tandem mass spectrometry for large-scale characterization of proteoforms in complex samples -- Assessment of macro- and microheterogeneity of monoclonal antibodies using Capillary Zone Electrophoresis hyphenated with Mass Spectrometry -- High Sensitivity Glycoproteomic Analysis of Biological Samples by CZE-ESI-MS -- Capillary Zone Electrophoresis-Electrospray Ionization Tandem Mass Spectrometry for Total Analysis of Chondroitin/Dermatan Sulfate Oligosaccharides -- In-Source Fragmentation for Identification of Compounds by CE-ESI-TOF in Human Plasma. L-Proline as case study -- Assessing the energy status of low numbers of mammalian cells by capillary electrophoresis-mass spectrometry -- Applications of Capillary Electrophoresis-Mass Spectrometry to Chiral Analysis -- Improved Sensitivity to Determine Antibiotic Residues in Chicken Meat by In-Line Solid-Phase Extraction coupled to Capillary Electrophoresis-Tandem Mass Spectrometry -- CE Coupled to ICP-MS and Single Particle ICP-MS for Nanoparticle Analysis. .
520 _aThis volume details aspects and applications of interfacing capillary electrophoresis (CE) with mass spectrometry (MS). Chapters guide readers through approaches based on different types of CE-MS interfaces such as (nano)sheath liquid, porous tip, and liquid junction, as well as various capillary coatings, and a broad range of applications including several top-down and bottom-up proteomic approaches. Additionally, a list of analyte targets was provided consisting of amphetamines, antibiotics, carbohydrates (including glycosaminoglycans and glycopeptides), enantiomers, extracellular matrix metabolites, monoclonal antibodies, and nanoparticles, and therefore covers numerous fields of applications such as pharmaceutical, biomedical, food, agrochemical, and environmental analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Capillary Electrophoresis-Mass Spectrometry: Methods and Protocols aims to provide highly valuable information for both beginners and experts in the field be it students, technical staff, and scientists.
988 _aSpringer_Protocols_2022
650 7 _2embne
_9688491
_aElectroforesis capilar
650 7 _2embne
_9141447
_aEspectrometría de masas
776 0 8 _iPrinted edition:
_z9781071624920
776 0 8 _iPrinted edition:
_z9781071624944
776 0 8 _iPrinted edition:
_z9781071624951
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2493-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b07/2023
_dz
_eb
_zSI