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008			220722s2022 xxu| o |||| 0|eng d
020			_a9781071625132
024	7		_a10.1007/978-1-0716-2513-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC271 .C5 _b2022 EB
245	0	0	_aCancer Drug Resistance : _bMethods and Protocols _cedited by Marta Baiocchi
250			_a1st edition 2022
264		1	_aNew York, NY _bSpringer International Publising _c2022
300			_a1 recurso en línea (XIII, 242 páginas) _b75 ilustraciones, 56 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2535
505	0		_aA 3D Biomimetic System for Testing Anticancer Drugs Sensitivity -- Patient-Derived Breast Cancer Tissue Cultures for Anti-Endocrine Drug Assays -- Co-Culture of Two Different Cell Lines in a Two-Layer Microfluidic Device -- Generation and Culture of Organotypic Breast Carcinoma Spheroids for the Study of Drug Response in a 3D Microfluidic Device -- A Methodological Workflow to Analyze Synthetic Lethality and Drug Synergism in Cancer Cells -- Establishment of In Vivo Acquired Resistance to Chemotherapy via Individual Dose Escalation Treatment Regime -- A Label Retaining System to Capture Slow Cycling Cancer Cells -- A Fast and Furious Liquid Biopsy Assay to Monitor Targeted Therapy Resistance -- Assessment of Tumor Heterogeneity in High-Grade Serous Ovarian Cancer: Mass Cytometry to Understand the Complex Tumor Biology -- Analysis of Transcriptomic Data Generated from Drug Treated Cancer Cell Line -- Simultaneous Mapping of Enhancers and Enhancer Rearrangements with Paired-End H3K27ac ChIP-seq -- Identification of Drug Resistance Mechanisms using Genome-Wide CRISPR-Cas9 Screens -- RNA Sequencing Data Analysis on the Maser Platform and the Tag-Count Comparison-Graphical User Interface -- Dissecting the Epigenomic Driving Drug Resistance by ATAC-Seq -- Polygenomic Interrogation of Drug Resistance Genes -- Analysis of ER-phagy in Cancer Drug Resistance -- Drug Target Prediction using Context-Specific Metabolic Models Reconstructed from rFastcormics.
520			_aThis volume discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Cancer Drug Resistance: Methods and Protocols is a valuable resource for all scientists and researchers who are looking to learn more about the latest developments in understanding and overcoming anticancer drug resistance. .
988			_aSpringer_Protocols_2022
650		4	_aCáncer _xQuimioterapia _9674463
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2513-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b08/2023 _dz _eh _zSI