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008			220627s2022 xxu| o |||| 0|eng d
020			_a9781071624890
024	7		_a10.1007/978-1-0716-2489-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP551 _b2022 EB
245	0	0	_aChemical Protein Synthesis _cedited by Xuechen Li
250			_a1st edition 2022
264		1	_aNew York, NY _bSpringer International Publising _c2022
300			_a1 recurso en línea (XI, 259 páginas) _b89 ilustraciones, 69 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2530
505	0		_aSulfated Glycoprotein Synthesis -- Total Chemical Synthesis of a SARS-CoV-2 Miniprotein Inhibitor LCB1 -- Serine/Threonine Ligation and Cysteine/Penicillamine Ligation -- Continuous-flow synthesis of N-Methylated Peptides via Generation of an Acyl N-Methylimidazolium Cation -- Covalent Reactive Peptides to Block Protein - Protein Interactions and Inhibit Microbe-Host Interaction -- Ynamide-Mediated Synthetic Approach to Thioamide Substituted Peptides -- Improved Handling of Peptide Segments Using Side Chain-Based "Helping Hand" Solubilizing Tools -- Helical Stabilization of Peptide Macrocycles by Stapled Architectures -- General solution to the preparation of ꞵ-thiolated/Selenolated Amino Acids Via Visible Light Catalyzed Asymmetric Giese reaction -- Side-chain Anchoring Strategies for the Synthesis of Peptide Thioesters and Selenoesters -- Preparation of Site-Specific Succinylated Histone Mimics to Investigate Its Impact On Nucleosome Dynamics -- Protein Synthesis Via Activated Cysteine-Directed Protein Ligation -- Sulfonium Tethered Peptide -- PAL-mediated Ligation for Protein and Cell-Surface Modification -- Development of a Glycoform Library-based Strategy to Decipher the Role of Protein Glycosylation -- A Selenium-Based Cysteine Surrogate for Protein Chemical Synthesis -- Removable Backbone Modification (RBM) Strategy for the Chemical Synthesis of Hydrophobic Peptides/Proteins. .
520			_aThis volume provides updated protocols for chemical protein synthesis. Chapters guide readers through development methods, strategies, and applications of protein chemical synthesis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Chemical Protein Synthesis aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. .
988			_aSpringer_Protocols_2022
650		7	_2embne _9139861 _aProteínas _vManuales de laboratorio
700	1		_aLi, Xuechen _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781071624883
776	0	8	_iPrinted edition: _z9781071624906
776	0	8	_iPrinted edition: _z9781071624913
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2489-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2023 _dz _eu _zSI