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008			220622s2022 xxu| o |||| 0|eng d
020			_a9781071624418
024	7		_a10.1007/978-1-0716-2441-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC271 .G45 _b2022 EB
245	0	0	_aGene Therapy of Cancer : _bMethods and Protocols _cedited by Wolfgang Walther
250			_a3rd edition 2022
264		1	_aNew York, NY _bSpringer International Publising _c2022
300			_a1 recurso en línea (XI, 342 páginas) _b65 ilustraciones, 47 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2521
505	0		_aBrief Introduction to Current Cancer Gene Therapy -- Minicircles for CAR T Cell Production by Sleeping Beauty Transposition - A Technological Overview -- Generation of CAR-T Cells with Sleeping Beauty Transposon Gene Transfer -- Generation of Redirected Engineered Human Chimeric Antigen Receptor (CAR) T cells -- TCR- and CAR-engineering of Primary Human T cells -- TCR Gene Therapy for Cancer -- Gene Gun Her2/neu DNA Vaccination: Evaluation of Vaccine Efficacy in a Syngeneic Her2/neu Mouse Tumor Model -- Construction of Minicircle Suicide Genes Coding for Ribosome-Inactivating Proteins -- Claudin-targeted Suicide Gene Therapy for Claudin-Overexpressing Tumor Cells by Using Modified Clostridium Perfringens Enterotoxin (CPE) -- Bioengineered RNA Therapy in Patient-Derived Organoids and Xenograft Mouse Models -- Application of Transcription Factor Decoy Oligodeoxynucleotides (ODNs) for Cancer Therapy -- NK Cell Effector Functions and Bystander Tumor Cell Killing in Immunovirotherapy -- A qPCR-based Method for Quantification of Replication Competent Adenovirus (RCA) in Conditionally Replicating Oncolytic Adenoviruses -- Visualized Cancer Immunotherapy with Engineered Salmonella typhimurium -- CANCER Gene Therapy: Development and Production Of Lentiviral Vectors For Gene Therapy -- Capillary Gel Electrophoresis (CGE) for Quality Control of Plasmid DNA in Gene Therapy: quality control of 20-years stored GMP-grade Plasmid DNA -- Efficient Generation of Superior Dumbbell-Shaped Non-viral DNA Delivery Vectors Using 1-2-3 Gap-primer PCR.
520			_aThis third edition provides new and updated chapters on gene therapeutic strategies of cancer. Chapters guide readers through suicide and oncolytic gene therapy, gene replacement and gene suppression therapy, vector development and refinement, immunogene therapy, TCR and CAR engineering, tumor vaccination using DNA or RNA vaccines, and antitumoral immune stimulation at different levels. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Gene Therapy of Cancer: Methods and Protocols, Third Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
988			_aSpringer_Protocols_2022
650		7	_2embne _9273952 _aCáncer _xAspectos genéticos _vManuales de laboratorio
650		7	_2embne _9150702 _aTerapia genética _xManuales de laboratorio
776	0	8	_iPrinted edition: _z9781071624401
776	0	8	_iPrinted edition: _z9781071624425
776	0	8	_iPrinted edition: _z9781071624432
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2441-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2023 _dz _eu _zSI