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008			230610s2022 xxu| o |||| 0|eng d
020			_a9781071616932
024	7		_a10.1007/978-1-0716-1693-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aR857 .B5 _b2022 EB
245	0	0	_aOrgan-on-a-Chip : _bMethods and Protocols _cedited by Marco Rasponi
250			_a1st edition 2022
264		1	_aNew York, NY _bSpringer International Publising _c2022
300			_a1 recurso en línea (XII, 322 páginas) _b83 ilustraciones, 71 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2373
505	0		_aPhoto and Soft Lithography for Organs-on-Chip applications -- Organs-on-chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices -- Thermoplastic microfluidics -- Bile Duct-On-a-Chip -- Establishment of a Modular Anaerobic Human Intestine Chip -- Intestinal Epithelium Tubules on a Chip -- A Human Neurovascular Unit On-a-chip -- Generation of a Glomerular Filtration Barrier on a Glomerulus-on-a-chip Platform -- Electro-Mechanical Stimulation of 3D Cardiac Microtissues in a heart-on-chip Model -- Miniaturized Vascularized Bleeding Model of Hemostasis -- Fabrication and Use of a Pumpless Microfluidic Lymphatic Vessel Chip -- On Chip-Platelet Activation Assessment: Microfluidic Emulation of Shear Stress Profiles Induced by Mechanical Circulatory Support Devices -- Biofabrication of 3D Human Muscle Model with Vascularization and Endomysium -- Mechanical induction of Osteoarthritis traits in a cartilage-on-chip model -- A Synovium/Cartilage-On-A-Chip Model To Investigate The Process Of Monocyte Extravasation -- A Mesoscale 3D Culture System For Native And Engineered Biphasic Tissues: Application To The Osteochondral Unit -- 3D biofabricated in Vitro Models of Vascularized and Mineralized Bone Tissues -- Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-On-Chip Technology. .
520			_aThis book provides a collection of microphysiological systems employed for chemical/drug screening and strategies to mimic various physiological conditions. Chapters guide readers through Organ-on-a-Chip( OoC) platforms such as liver, intestine, blood-brain barrier, kidney, vessels, cardiac and skeletal muscles, articular joint, human fat. Additional chapters detail microfabrication technologies used to fabricate OoC devices such as, standard photo- and soft-lithography, techniques to fabricate membranes, and industrial-oriented fabrication methods.Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Organ-On-a Chip: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field.
988			_aSpringer_Protocols_2022
650		7	_2embne _9143820 _aIngeniería biomédica
650		7	_2embne _9667809 _aElectrónica médica
776	0	8	_iPrinted edition: _z9781071616925
776	0	8	_iPrinted edition: _z9781071616949
776	0	8	_iPrinted edition: _z9781071616956
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1693-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b06/2023 _dz _eIG _zSI