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008			220910s2022 xxua o |||| 0|eng d
020			_a9781071627129
024	7		_a10.1007/978-1-0716-2712-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR185.8 .T2 _b2022 EB
245	0	0	_aT-Cell Repertoire Characterization _cedited by Huang Huang, Mark M. Davis
250			_a1st edition 2022
264		1	_aNew York, NY _bSpringer International Publising _c2022
300			_a1 recurso en línea (XII, 391 páginas) _b73 ilustraciones, 67 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2574
505	0		_aLigand identification for Orphan MHC-agnostic T-cell receptors by whole genome CRISPR-Cas9 screening -- Discovery of HLA-E-presented epitopes: MHC-E/peptide binding and T cell recognition -- Identification of human antigen-specific T cells using class II MHC tetramer staining and enrichment -- Characterization of KIR+CD8+ regulatory T cells in humans by scRNA- and TCR-seq -- Detection of α-synuclein-specific T cells in Parkinson's disease -- The intra-tumoural T cell receptor repertoire - steps towards a useful clinical biomarker -- Enriching and Characterizing T-Cell Repertoires from 3' Barcoded Single-Cell Whole Transcriptome Amplification Products -- Tetramer associated T cell receptor sequencing -- T-cell Repertoire Characterization -- Characterization of mouse CD4 TCR and its targeting antigen -- Rapid identification of MHCII-binding peptides through microsphere-assisted peptide screening (MAPS) -- A high throughput strategy for T-Cell Receptor cloning and expression -- Epitope-specific T-cell receptor data and tools in the Immune Epitope Database -- A Bioinformatic Framework for Dissecting the Dynamics of T cells from Single-Cell Transcriptome -- Grouping T-Cell Antigen Receptors by Specificity -- Flexible Distance-Based TCR Analysis in Python with tcrdist3 -- Multimodal T cell analysis with CoNGA.
520			_aThis volume provides a comprehensive compilation of protocols in T cell repertoire analysis, from the leading experts in the field, representing both well-established methods and cutting-edge advances. Chapters broadly cover the emerging new T cell subsets, sequencing technologies for capturing TCR repertoire, and computational tools for analyzing an ever-growing TCR repertoire, with a particular focus on how to link the sequence with TCR antigen specificity. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T-Cell Repertoire Characterization aims to be a useful practical guide to researches to help further their study in this field. .
988			_aSpringer_Protocols_2022
650		7	_2embne _9144344 _aLinfocitos T
650		7	_2embne _9138330 _aInmunología
650		7	_2embne _9139477 _aCitología
776	0	8	_iPrinted edition: _z9781071627112
776	0	8	_iPrinted edition: _z9781071627136
776	0	8	_iPrinted edition: _z9781071627143
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2712-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b06/2023 _dz _eb _zSI