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020 _a9781071625736
024 7 _a10.1007/978-1-0716-2573-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRM301.3 .G45
_b2022 EB
245 0 0 _aPharmacogenomics in Drug Discovery and Development
_cedited by Qing Yan
250 _a3rd edition 2022
264 1 _aNew York, NY
_bSpringer International Publising
_c2022
300 _a1 recurso en línea (XIV, 616 páginas)
_b54 ilustraciones, 47 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2547
505 0 _aTarget Discovery for Drug Development Using Mendelian Randomization -- Human Leukocyte Antigen (HLA) Testing in Pharmacogenomics -- Pharmacogenomics in Targeted Therapy and Supportive Care Therapies for Cancer -- Pharmacogenomics in Cytotoxic Chemotherapy of Cancer -- Management of Side Effects in the Personalized Medicine Era: Chemotherapy-Induced Peripheral Neuropathy -- The Yin-Yang Dynamics in Cancer Pharmacogenomics and Personalized Medicine -- Design of Personalized Neoantigen RNA Vaccines Against Cancer Based on Next Generation Sequencing Data -- COVID-19 Pharmacotherapy: Drug Development, Repurposing of Drugs, and the Role of Pharmacogenomics -- Pharmacogenomics Informs Cardiovascular Pharmacotherapy -- Pharmacogenomic Screening of Patient-Specific hiPSC-Derived Cardiomyocyte Drug Candidates Using High-Throughput Calcium Imaging -- The Yin-Yang Dynamics in Cardiovascular Pharmacogenomics and Personalized Medicine -- GTPgS Assay for Measuring Agonist-Induced Desensitization of Two Human Polymorphic Alpha2B-Adrenoceptor Variants -- Pharmacogenomics of Alzheimer's Disease: Novel Strategies for Drug Utilization and Development -- Pharmacogenetics of Antipsychotic Treatment in Schizophrenia -- The Pharmacogenetic Impact on the Pharmacokinetics of ADHD Medications -- Pharmacogenetics of Addiction Therapy -- Pharmacogenomics of Opioid Treatment for Pain Management -- The Role of Pharmacogenomics in Postoperative Pain Management -- Pharmacogenetics of Drug Therapies in Rheumatoid Arthritis -- Pharmacogenomics in Children -- Genetic Ancestry Inference for Pharmacogenomics.
520 _aThis new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.
988 _aSpringer_Protocols_2022
650 7 _2embne
_9165192
_aFarmacogenómica
650 7 _2embne
_9141808
_aQuímica farmacéutica
776 0 8 _iPrinted edition:
_z9781071625729
776 0 8 _iPrinted edition:
_z9781071625743
776 0 8 _iPrinted edition:
_z9781071625750
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2573-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b06/2023
_dz
_eb
_zSI