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008			220824s2022 xxua o |||| 0|eng d
020			_a9781071625095
024	7		_a10.1007/978-1-0716-2509-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRM666 .P835 _b2022 EB
245	0	0	_aBiosafety Assessment of Probiotic Potential _cedited by Mitesh Kumar Dwivedi, Natarajan Amaresan, A. Sankaranarayanan, Rasheedunnisa Begum
250			_a1st edition 2022
264		1	_aNew York, NY _bSpringer International Publising _c2022
300			_a1 recurso en línea (XVII, 412 páginas) _b35 ilustraciones, 19 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods and Protocols in Food Science _x2662-9518
505	0		_aDetermination of biogenic Amine Production -- Determination of Gelatinases,Glycosidases, and Enolase production -- Determination of β-Glucuronidase Production -- Determination of Nitroreductase Production -- Determination of Azoreductase production -- Determination of Hemolytic activity -- Determination of DNAse Activity -- Determination of Bile Salts Deconjugation -- Determination of D-lactic Acid Production -- Determination of Antibiotic Resistance -- Determination of Antibiotic Resistance Gene Transfer -- Determination of Toxin Production -- Detection of Toxin Genes by PCR Based Methods -- Determination of Presence of Plasmids and Virulence and Structural Genes -- Determination of Toxicity through Cytotoxicity Assays -- In vitro Evaluation of the Nitric Oxide Pathway -- Assessment of Capsule Formation -- Assessment of Platelet aggregation -- Assessment of Fibrinogen and Fibronectin Binding Activity -- Assessment of Probiotics Adhesion to Mammalian Cells -- Assessment of Mutagenicity -- Assessment of Induction and Destruction of Thrombi -- Assessment of degradation of mucin -- Evaluation of General Health Status of the Animals during the in-Life Phase -- Assessment of Bacterial Translocation Through Blood Cultures -- Determination of Splenic weight index and Weight-to-length ratio -- Determination of Total liver glutathione and plasma malondialdehyde concentrations -- Determination of Serum Lactate and Fecal Calprotectin for Assessing The Intestinal Inflammation -- In vivo Evaluation of Adhesion properties of Probiotics -- Determination of Streptomyces Probiotics oral administration in broiler chicken -- Determination of infectivity of probiotics using animal models -- Determination of Infectivity of Probiotics using Immunosuppressed Hosts -- Assessment of Reproductive toxicity -- Assessment of Developmental toxicity in Zebrafish model -- Assessment of Inflammation in Animal Models (Macroscopic Or Histological Inflammation In The Ileum Or In The Colon) -- Assessment of inflammation in animal models (Quantification of TNFA, IFNG, IL4, and IL10 mRNAs by Real-time PCR) -- Assessment of inflammation in animal models (Quantification of TNF-α, IFN-γ, IL-4, & IL-10 proteins by ELISA) -- Detection of Myeloperoxidase activity by Enzyme Linked Immunosorbent Assay -- Assessment of Bacterial Translocation Through Mesenteric Lymph Nodes [MLN] and Spleen Cultures.
520			_aThis volume provides methods on procedures for assessing the biosafety aspects of probiotics. Chapters are divided into five parts detailing in vitro biosafety assessment, biogenic amine production, D-lactic acid production, toxin production, production of various enzymes, determination of toxicity, mutagenicity, virulence genes, capsule formation, hemolytic activity, DNAse activity, bile salt deconjugation, antibiotic resistance, antibiotic resistance gene transfer, mucin degradation, platelet aggregation, and in vivo biosafety assessment of probiotics including determination of infectivity, reproductive and developmental toxicity, and evaluation of immunological parameters in animal models. Authoritative and cutting-edge, Biosafety Assessment of Probiotic Potential aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field. .
988			_aSpringer_Protocols_2022
650		7	_2embne _9161029 _aProbióticos
650		7	_2embne _9140931 _aBiotecnología
776	0	8	_iPrinted edition: _z9781071625088
776	0	8	_iPrinted edition: _z9781071625101
776	0	8	_iPrinted edition: _z9781071625118
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-2509-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b06/2023 _dz _eb _zSI