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008			230121s2022 sz | s |||| 0|eng d
020			_a9783030238100
024	7		_a10.1007/978-3-030-23810-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP379 _b2022 EB
245	0	0	_aHandbook of the Cerebellum and Cerebellar Disorders _cedited by Mario U. Manto, Donna L. Gruol, Jeremy D. Schmahmann, Noriyuki Koibuchi, Roy V. Sillitoe
250			_a2nd edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (512 illus., 321 illus. in color. eReference.
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_aChapter 1. Embryology -- Chapter 2. Anatomy -- Chapter 3. Neuroimaging of the cerebellum -- Chapter 4. Neurotransmitters and neuromodulators -- Chapter 5. Fructose metabolism and the cerebellum -- Chapter 6. Physiology of the cerebellum -- Chapter 7. Cerebellum and pain processing -- Chapter 8. Computational models of cerebellar function -- Chapter 9. Animal models of cerebellar ataxias -- Chapter 10. Symptoms of cerebellar disorders in human -- Chapter 11. Clinical deficits -- Chapter 12. Cerebellum and cognitive processes -- Chapter 13. Cerebellum and emotion regulation -- Chapter 14. Developmental disorders -- Chapter 15. Autism spectrum disorders and ataxia -- Chapter 16. Cerebellum and schizophrenia -- Chapter 17. Progressive myoclonic epilepsies -- Chapter 18. Cerebellar stroke -- Chapter 19. Immune diseases -- Chapter 20. Endocrine disorders -- Chapter 21. Infectious diseases -- Chapter 22. Tumors and paraneoplastic disorders -- Chapter 23. Trauma of the posterior fossa -- Chapter 24. Cerebellotoxic agents -- Chapter 25. Multiple system atrophy (MSA) -- Chapter 26. Essential tremor -- Chapter 27. Autosomal Recessive Cerebellar Ataxias (ARCAs) -- Chapter 28. Mitochondrial disorders -- Chapter 29. X-linked ataxias -- Chapter 30. Dominant ataxias -- Chapter 31. Overview of the differential diagnosis of cerebellar disorders -- Chapter 32. Overview of the general management of cerebellar disorders.
520			_aOur knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.
988			_aSpringer_BiomedLife_2022
650		7	_9151993 _aCerebelo _xEnfermedades
650		7	_2embne _9139040 _aNeurología
700	1		_984532 _aManto, Mario _eautor
700	1		_986019 _aGruol, Donna L. _eautor
700	1		_986018 _aSchmahmann, Jeremy D _eautor
700	1		_aKoibuchi, Noriyuki _eautor _986020
700	1		_9686076 _aSillitoe, Roy V. _eautor
776	0	8	_iPrinted edition: _z9783030238094
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-23810-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2023 _dz _eIG _zSI