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008			211201s2022 sz a o |||| 0|eng d
020			_a9783030847449
024	7		_a10.1007/978-3-030-84744-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC925 _b2022 EB
245	0	0	_aOrthobiologics : _bInjectable Therapies for the Musculoskeletal System _cedited by Giuseppe Filardo, Bert R. Mandelbaum, George F. Muschler, Scott A. Rodeo, Norimasa Nakamura
250			_a1st edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XI, 402 páginas) _b73 ilustraciones, 66 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_aI. Injectable OrthoBiologics: Formulations and Rationale 1. Bone marrow-derived cultured stromal cells and Bone Marrow Concentrate -- 2. Adipose-derived cultured stromal cells and Stromal Vascular Fraction from adipose tissue -- 3. Synovial-derived cultured stromal cells -- 4. Amniotic, Placenta, and Umbilical cord-derived cultured stromal cells -- 5. Allogeneic cells: pros and cons -- 6. Steroid hormones -- 7. Cytokines, chemokines, alpha-2-macroglobulin, growth factors -- 8. Platelet-rich plasma: leucocyte-rich, leukocyte-poor, autologous conditioned serum, autologous protein solution -- 9. Amniotic tissue extract, placenta tissue extract -- 10. Extracellular vesicles (exosomes) -- II. Injectable OrthoBiolologics: evaluation methods and results based on pathology and anatomy -- 11. Rotator cuff tendinopathy: cell therapy -- 12. Rotator cuff tendinopathy: biologics -- 13. Tennis elbow: cell therapy -- 14. Tennis elbow: cell therapy biologics -- 15. Patellar tendinopathy: cell therapy -- 16. Patellar tendinopathy: biologics -- 17. Achilles tendinopathy: cell therapy -- 18. Achilles tendinopathy: biologics -- 19. Plantar Fasciitis: cell therapy -- 20. Plantar Fasciitis: biologics -- 21. Ligament lesions: cell therapy -- 22. Ligament lesions: biologics -- 23. Meniscal lesions: cell therapy -- 24. Meniscal lesions: biologics -- 25. Muscle lesions: cell therapy -- 26. Muscle lesions: biologics -- 27. Fractures (incl. Nonunions): cell therapy -- 28. Fractures (incl. Nonunions): biologics -- 29. Cartilage lesions and Osteoarthritis of the knee: cell therapy -- 30. Cartilage lesions and Osteoarthritis of the knee: biologics -- 31. Cartilage lesions and Osteoarthritis of the hip and ankle: cell therapy -- 32. Cartilage lesions and Osteoarthritis of the hip and ankle: biologics -- III. Future directions 33. Pluripotent stem cells: Embryonic/Fetal stem cells and induced pluripotent stem (iPS) cells -- 34. Gene therapy -- 35. Stimulation of the intrinsic stromal cell niche -- 36 Conclusions.
520			_aThis book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies - ranging from tendinopathies through non-unions to articular degenerative processes - as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
988			_aSpringer_Medicine_2022
650		7	_2embne _9181875 _aAparato locomotor _xEnfermedades _xTratamiento
650		7	_2embne _9204610 _aAparato locomotor _xHeridas y lesiones _xTratamiento
776	0	8	_iPrinted edition: _z9783030847432
776	0	8	_iPrinted edition: _z9783030847456
776	0	8	_iPrinted edition: _z9783030847463
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-84744-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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998			_b01/2023 _dz _eb _zSI