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020 _a9783030971823
024 7 _a10.1007/978-3-030-97182-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aNeuroproteomics as a Tool for Understanding Schizophrenia
_cedited by Daniel Martins-de-Souza
250 _a1st edition 2022
264 1 _aCham
_bSpringer International Publishing
_c2022
300 _a1 recurso en línea (VIII, 143 páginas)
_b12 ilustraciones, 11 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aProteomics Metabolomics Interactomics and Systems Biology
_x2730-6224
_v1400
505 0 _a1. Postmortem brains: what can proteomics tell us about the sources of schizophrenia? -- 2. What can we learn from animal models to study schizophrenia? -- 3. Modeling schizophrenia in vitro: challenges and insights on studying brain cell -- 4. Schizophrenia outside the brain -- 5. Molecular features triggered by antipsychotic medication in brain cells -- 6. Known and Unexplored Post-Translational Modification Pathways in Schizophrenia -- 7. Molecular findings guiding the modulation of the endocannabinoid system as a potential target to treat schizophrenia -- 8. Metabolomics: A powerful tool to understand the schizophrenia biology -- 9. Modulating specific pathways in vitro to understand the synaptic dysfunction of schizophrenia -- 10. Proteomics and schizophrenia: the evolution of a great partnership.
520 _aOver the past decade, neuroproteomics has shed light on the molecular features of schizophrenia by depicting biological processes involved with its establishment, maintenance and treatment. These studies have also pointed to potential biomarkers applicable to diagnosis and medication monitoring. Edited by a leader in the field of neuroproteomics with contributions from subject experts, this new volume will address recent findings and compile evidence from difference perspectives-such as human samples, animal models, pluripotent stem cell-derived in vitro pre-clinical models-and provide findings to inform the development of innovative future treatment strategies. This volume will be useful for a broad audience of researchers and professionals, including biologists, neurologists, psychiatrists, analytical chemists, and pharmacists, among others. Provides comprehensive overview on how neuroproteomics helped depicting the molecular features of schizophrenia Addresses biological processes, treatment strategies, and recent research findings associated to schizophrenia Addresses current research challenges, future strategies, and clinical applications.
700 1 _aMartins-de-Souza, Daniel
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030971816
776 0 8 _iPrinted edition:
_z9783030971830
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-97182-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
988 _aSpringer_BiomedLife_2022
999 _c394869
_d394869